TY  - GEN
N2  - Acute cardiac injury with renal injury (acute cardiorenal syndrome) can induce chronic kidney disease (CKD), but mechanisms by which heart injury signals to kidney are unclear. Cardiac LIM protein (CSRP3) is a cardiomyocyte differentiation factor which is released into plasma after cardiac arrest. We hypothesized that CSRP3 induces myogenesis in the renal proximal tubule, inducing CKD.
DO  - 10.6083/bpxhc41331
DO  - doi
AB  - Acute cardiac injury with renal injury (acute cardiorenal syndrome) can induce chronic kidney disease (CKD), but mechanisms by which heart injury signals to kidney are unclear. Cardiac LIM protein (CSRP3) is a cardiomyocyte differentiation factor which is released into plasma after cardiac arrest. We hypothesized that CSRP3 induces myogenesis in the renal proximal tubule, inducing CKD.
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
T1  - Cardiac cysteine and glycine rich protein 3 (CSRP3) induces renal myogenesis leading to CKD
ED  - Hutchens, Michael
DA  - 2023-07-21
AU  - Funahashi, Yoshio
AU  - Hebert, Jessica
AU  - Munhall, Adam
AU  - Groat, Tahnee
AU  - Hutchens, Michael
L1  - https://digitalcollections.ohsu.edu/record/41331/files/ResearchWeek.2023.Funahashi.Yoshio%20.pdf
PB  - Oregon Health and Science University
LA  - eng
PY  - 2023-07-21
ID  - 41331
L4  - https://digitalcollections.ohsu.edu/record/41331/files/ResearchWeek.2023.Funahashi.Yoshio%20.pdf
KW  - Pathology
KW  - Molecular Biology
KW  - Cell Biology
KW  - Hypertension
KW  - Cardio-Renal Syndrome
KW  - Acute Kidney Injury
KW  - Fibrosis
KW  - Heart Arrest
KW  - Heart Injuries
KW  - chronic kidney disease
KW  - csrp3
KW  - cardiorenal syndrome, type 1
TI  - Cardiac cysteine and glycine rich protein 3 (CSRP3) induces renal myogenesis leading to CKD
Y1  - 2023-07-21
L2  - https://digitalcollections.ohsu.edu/record/41331/files/ResearchWeek.2023.Funahashi.Yoshio%20.pdf
LK  - https://digitalcollections.ohsu.edu/record/41331/files/ResearchWeek.2023.Funahashi.Yoshio%20.pdf
UR  - https://digitalcollections.ohsu.edu/record/41331/files/ResearchWeek.2023.Funahashi.Yoshio%20.pdf
ER  -