000041331 001__ 41331
000041331 005__ 20240328094023.0
000041331 0247_ $$2doi$$a10.6083/bpxhc41331
000041331 037__ $$aIR
000041331 041__ $$aeng
000041331 245__ $$aCardiac cysteine and glycine rich protein 3 (CSRP3) induces renal myogenesis leading to CKD
000041331 260__ $$bOregon Health and Science University
000041331 269__ $$a2023-07-21
000041331 336__ $$aAbstract
000041331 520__ $$aAcute cardiac injury with renal injury (acute cardiorenal syndrome) can induce chronic kidney disease (CKD), but mechanisms by which heart injury signals to kidney are unclear. Cardiac LIM protein (CSRP3) is a cardiomyocyte differentiation factor which is released into plasma after cardiac arrest. We hypothesized that CSRP3 induces myogenesis in the renal proximal tubule, inducing CKD.
000041331 540__ $$fCC BY
000041331 542__ $$fIn copyright - joint owners
000041331 650__ $$aPathology$$023652
000041331 650__ $$aMolecular Biology$$022384
000041331 650__ $$aCell Biology$$017350
000041331 650__ $$aHypertension$$020538
000041331 650__ $$aCardio-Renal Syndrome$$039549
000041331 650__ $$aAcute Kidney Injury$$039113
000041331 650__ $$aFibrosis$$019028
000041331 650__ $$aHeart Arrest$$019929
000041331 650__ $$aHeart Injuries$$019941
000041331 6531_ $$achronic kidney disease
000041331 6531_ $$acsrp3
000041331 6531_ $$acardiorenal syndrome, type 1
000041331 691__ $$aSchool of Medicine$$041369
000041331 692__ $$aDepartment of Anesthesiology and Perioperative Medicine$$041393
000041331 7001_ $$aFunahashi, Yoshio$$uOregon Health and Science University$$041354
000041331 7001_ $$aHebert, Jessica$$uOregon Health and Science University$$041354
000041331 7001_ $$aMunhall, Adam$$uOregon Health and Science University$$041354
000041331 7001_ $$aGroat, Tahnee$$uOregon Health and Science University$$041354
000041331 7001_ $$aHutchens, Michael$$uOregon Health and Science University$$041354
000041331 711__ $$aResearch Week$$uOregon Health and Science University$$d2023
000041331 7201_ $$aHutchens, Michael$$uOregon Health and Science University$$041354$$7Personal
000041331 8564_ $$9388d5acd-8fac-494c-a12a-3733e8a95825$$s177098$$uhttps://digitalcollections.ohsu.edu/record/41331/files/ResearchWeek.2023.Funahashi.Yoshio%20.pdf
000041331 980__ $$aResearch Week
000041331 981__ $$aPublished$$b2023-07-21