@article{IR,
      author = {Gladen Kolarsky, Noah and Hack, Wyatt and Maitra, Urmila  and Ciesla, Lukasz and Gray, Nora},
      url = {http://digitalcollections.ohsu.edu/record/41333},
      title = {Gardenin A decreases neuroinflammation, activates  antioxidant response and improves cognitive and motor  function in A53T alpha synuclein overexpressing mice},
      publisher = {Oregon Health and Science University},
      abstract = {Oxidative stress and neuroinflammation are widespread in  the Parkinson’s disease (PD) brain and contribute to the  synaptic degradation and dopaminergic cell loss that result  in cognitive impairment and motor dysfunction. The compound  Gardenin A (GA) has been shown to activate the  NRF2-regulated antioxidant pathway and inhibit the  NFkB-regulated pro-inflammatory pathway in a Drosophila  model of PD.  Here, we evaluate the effects of GA on A53T  alpha-synuclein overexpressing (A53TSyn) mice.},
      number = {IR},
      doi = {https://doi.org/10.6083/bpxhc41333},
      recid = {41333},
      address = {2023-07-21},
}