@article{ETD,
      school = {Ph.D.},
      author = {Caruso, Breanna},
      url = {http://digitalcollections.ohsu.edu/record/41548},
      title = {Modulating T cell development with implications for  response to immune checkpoint blockade},
      publisher = {Oregon Health and Science University},
      abstract = {Immune checkpoint blockade (ICB) has revolutionized the  ways in which we treat some cancers, producing durable  responses. However, many patients fail to respond to ICB.  It is theorized that patients require tumor-specific T  cells to respond effectively to ICB, but aged individuals  have compromised T cell diversity partially due to reduced  thymic output. The goal of this dissertation is to  determine the role of a common target of ICB, programmed  cell death protein 1 (PD-1), in regulating T cell  development in the thymus.},
      number = {ETD},
      doi = {https://doi.org/10.6083/bpxhc41548},
      recid = {41548},
      address = {2023-08-16},
}