000041613 001__ 41613
000041613 005__ 20240418151034.0
000041613 0247_ $$2doi$$a10.6083/bpxhc41613
000041613 037__ $$aIR
000041613 041__ $$aeng
000041613 245__ $$aVibration to restore presynaptic inhibition and alleviate start hesitation in people with Parkinson’s disease and freezing of gait: a study protocol
000041613 260__ $$bOregon Health and Science University
000041613 269__ $$a2023-08-21
000041613 336__ $$aAbstract
000041613 520__ $$aFreezing of gait (FOG) is one of the most debilitating features of Parkinson’s disease (PD). FOG may be due to a lack of central inhibition, as people with PD and FOG (PD+FOG) have difficulty inhibiting postural preparation prior to initiating stepping. We recently demonstrated that presynaptic inhibition (PSI) in the spinal cord, is crucial for coordinating postural preparation with step initiation. To investigate the feasibility of vibrotactile feedback in restoring PSI and overcome step initiation failure in PD+FOG.
000041613 540__ $$fCC BY
000041613 542__ $$fIn copyright - joint owners
000041613 650__ $$aGait Disorders, Neurologic$$032249
000041613 650__ $$aVibration$$027806
000041613 650__ $$aParkinson Disease$$023617
000041613 650__ $$aFeedback$$018928
000041613 650__ $$aGoals$$019673
000041613 650__ $$aHumans$$020376
000041613 650__ $$aParkinsonian Disorders$$032648
000041613 650__ $$aMovement Disorders$$022476
000041613 650__ $$aGait$$019340
000041613 650__ $$avibrotactile stimulation
000041613 6531_ $$afreezing of gait
000041613 6531_ $$apresynaptic inhibition
000041613 691__ $$aSchool of Medicine$$041369
000041613 692__ $$aDepartment of Neurology$$041431
000041613 7001_ $$aChitlur, Tanisha$$uOregon Health and Science University$$041354
000041613 7001_ $$aLiu, William$$uOregon Health and Science University$$041354
000041613 7001_ $$aBoari, Daniel$$uFederal University of ABC
000041613 7001_ $$aHorak, Fay B.$$uOregon Health and Science University$$041354
000041613 7001_ $$aMancini, Martina$$uOregon Health and Science University$$041354
000041613 7001_ $$aSilva-Batista, Carla$$uOregon Health and Science University$$041354
000041613 711__ $$aResearch Week$$uOregon Health and Science University$$d2023
000041613 8564_ $$906653fcc-8a8a-432e-8a14-ada634953654$$s62612$$uhttps://digitalcollections.ohsu.edu/record/41613/files/ResearchWeek.2023.Chitlur.Tanisha.pdf
000041613 980__ $$aResearch Week
000041613 981__ $$aPublished$$b2023-08-21