TY  - GEN
N2  - Carcinoid tumors are neuroendocrine tumors which release prostaglandins and biogenic amines that can impact the cardiovascular system.1 In consequence, patients with metastatic disease can develop carcinoid syndrome characterized by flushing, tachycardia and syncope. The physiologic mechanisms that contribute to this hemodynamic instability are not well understood. Therefore, our study sought to establish a mouse model of carcinoid tumor metastasis that could be used to assess cardiovascular function.
DO  - 10.6083/bpxhc41619
DO  - doi
AB  - Carcinoid tumors are neuroendocrine tumors which release prostaglandins and biogenic amines that can impact the cardiovascular system.1 In consequence, patients with metastatic disease can develop carcinoid syndrome characterized by flushing, tachycardia and syncope. The physiologic mechanisms that contribute to this hemodynamic instability are not well understood. Therefore, our study sought to establish a mouse model of carcinoid tumor metastasis that could be used to assess cardiovascular function.
AD  - Western University of Health Sciences, COMP-NW
T1  - Cardiac function in a mouse model of carcinoid disease
ED  - Pommier, Rodney
ED  - Collaborator
DA  - 2023-08-21
AU  - Penrose, Sofia
AU  - Kuehn, Sydney
AU  - McCully,  Belinda
L1  - https://digitalcollections.ohsu.edu/record/41619/files/ResearchWeek.2023.Penrose.So%EF%AC%81a.pdf
PB  - Oregon Health and Science University
LA  - eng
PY  - 2023-08-21
ID  - 41619
L4  - https://digitalcollections.ohsu.edu/record/41619/files/ResearchWeek.2023.Penrose.So%EF%AC%81a.pdf
KW  - Carcinoid Heart Disease
KW  - Malignant Carcinoid Syndrome
KW  - Disease Models, Animal
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Liver Neoplasms
KW  - Neoplasm Metastasis
KW  - Carcinoid Tumor
KW  - Neuroendocrine Tumors
KW  - liver cancer
KW  - rodent models
TI  - Cardiac function in a mouse model of carcinoid disease
Y1  - 2023-08-21
L2  - https://digitalcollections.ohsu.edu/record/41619/files/ResearchWeek.2023.Penrose.So%EF%AC%81a.pdf
LK  - https://digitalcollections.ohsu.edu/record/41619/files/ResearchWeek.2023.Penrose.So%EF%AC%81a.pdf
UR  - https://digitalcollections.ohsu.edu/record/41619/files/ResearchWeek.2023.Penrose.So%EF%AC%81a.pdf
ER  -