000041630 001__ 41630
000041630 005__ 20240329102421.0
000041630 0247_ $$2doi$$a10.6083/bpxhc41630
000041630 037__ $$aIR
000041630 041__ $$aeng
000041630 245__ $$aCommensal glycerol metabolism determines oral niche development
000041630 260__ $$bOregon Health and Science University
000041630 269__ $$a2023-08-23
000041630 336__ $$aAbstract
000041630 520__ $$aThe oral microbiome has co-evolved and coexisted in a symbiotic relationship within their own ecology and with the host. Understanding the oral ecosystem and how it promotes a balanced microbiome, is essential to effectively maintain or restore oral health. Of over 700 bacterial taxa, commensals Streptococcus and Corynebacterium are two of the most prevalent members of the oral microbiome. Surprisingly, the inter-species interactions between both commensals and the effect of such interactions on dental diseases have never been investigated. Therefore, in this study, we aim to understand the molecular mechanism(s) between different taxa interactions, in particularly, Corynebacterium durum and Streptococcus sanguinis, and the implications on oral diseases.
000041630 540__ $$fCC BY
000041630 542__ $$fIn copyright - joint owners
000041630 650__ $$aGlycerol Kinase$$019625
000041630 650__ $$aFatty Acids$$018911
000041630 6531_ $$aoral microbiome
000041630 6531_ $$aglycerol dehydrogenase
000041630 6531_ $$amembrane vesicles
000041630 6531_ $$asymbiotic interaction
000041630 691__ $$aSchool of Dentistry$$041368
000041630 692__ $$aDepartment of Restorative Dentistry$$041446
000041630 7001_ $$aTreerat, June$$uOregon Health and Science University$$041354
000041630 7001_ $$aAnderson, David$$uOregon Health and Science University$$041354
000041630 7001_ $$aGiacaman, Rodrigo A.$$uUniversity of Talca. Chile
000041630 711__ $$aResearch Week$$uOregon Health and Science University$$d2023
000041630 8564_ $$936c20ebc-14c3-4664-bec9-ed90c06d0045$$s173369$$uhttps://digitalcollections.ohsu.edu/record/41630/files/ResearchWeek.2023.Treerat.June.pdf
000041630 980__ $$aResearch Week
000041630 981__ $$aPublished$$b2023-08-23