000000418 001__ 418 000000418 005__ 20260410124446.0 000000418 0247_ $$2DOI$$a10.6083/M4V9861N 000000418 037__ $$aETD 000000418 245__ $$aAdolescents receiving chemotherapy sleep, symptoms, and quality of life 000000418 260__ $$bOregon Health and Science University 000000418 269__ $$a2008 000000418 336__ $$aDissertation 000000418 502__ $$bPh.D. 000000418 520__ $$aThis dissertation describes nocturnal sleep–wake patterns in adolescents undergoing chemotherapy and examines relationships among sleep, treatment‑related symptoms, and quality of life. Fifty‑one adolescents with cancer were assessed using both objective actigraphy and self‑report sleep measures, along with standardized symptom and quality‑of‑life instruments. Results revealed delayed bedtimes, fragmented sleep, and reduced sleep efficiency, with fatigue, nausea, and pain among the most common and distressing symptoms. Sleep measures were not significantly associated with symptoms or quality of life; however, greater symptom burden was linked to poorer quality of life. Findings suggest that sleep disruption in this population is characterized more by fragmentation than by reduced sleep duration and highlight the value of actigraphy for clinical assessment. 000000418 540__ $$fCC BY 000000418 542__ $$fIn copyright - single owner 000000418 650__ $$aDrug Therapy$$018086 000000418 650__ $$aNeoplasms$$022758 000000418 650__ $$aChild$$016462 000000418 650__ $$aAdolescent$$014285 000000418 650__ $$aSymptom Burden 000000418 650__ $$aActigraphy$$038545 000000418 650__ $$aQuality of Life$$025032 000000418 650__ $$aSleep Wake Disorders$$026069 000000418 651__ $$aNorthwestern United States$$041197 000000418 6531_ $$achemotherapy 000000418 691__ $$aSchool of Nursing$$041370 000000418 7001_ $$aJohnson, Amy$$uOregon Health and Science University$$041354 000000418 8564_ $$9c1a988ae-ad14-4ce8-8ad5-2fe0b35f1aef$$s475560$$uhttps://digitalcollections.ohsu.edu/record/418/files/419_etd.pdf$$ePublic$$25b4d0e68c398c546a7d89d7a7f523e84$$31 000000418 901__ $$a<p>These documents are archival records. They are retained for historical reference only. </p><p><b>Need an accessible version? Use the ‘Get Accessible Copy’ link above.</b></p> 000000418 905__ $$a/rest/prod/t1/48/fh/17/t148fh17x 000000418 909CO $$ooai:digitalcollections.ohsu.edu:418$$pstudent-work 000000418 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument 000000418 980__ $$aTheses and Dissertations