TY  - GEN
N2  - Bone defects can occur after trauma, infection, or oncologic resection and autologous bone grafting is the current treatment option. However, this method has its limitations in more severe injuries as it may cause infection and scarring at donor sites. Thus, developing biomaterials that are osteoinductive with live cells is essential for treating bone defects.   We are creating a bone-like structure that are biomineralized to the nanoscale level and embedded with human mesenchymal stem cells (hMSCs) that undergo osteogenic differentiation without any conventional supplements.
DO  - 10.6083/bpxhc41886
DO  - doi
AB  - Bone defects can occur after trauma, infection, or oncologic resection and autologous bone grafting is the current treatment option. However, this method has its limitations in more severe injuries as it may cause infection and scarring at donor sites. Thus, developing biomaterials that are osteoinductive with live cells is essential for treating bone defects.   We are creating a bone-like structure that are biomineralized to the nanoscale level and embedded with human mesenchymal stem cells (hMSCs) that undergo osteogenic differentiation without any conventional supplements.
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
T1  - Faster biomineralization and osteogenesis on-a-chip  using 3D bioprinting and microfluidics
DA  - 2023-09-12
AU  - Visalakshan, Rahul M.
AU  - Sousa, Mauricio
AU  - Taheri, Anthony
AU  - Athirasala, Avathamsa
AU  - Bertassoni, Luiz
L1  - https://digitalcollections.ohsu.edu/record/41886/files/ResearchWeek.2023.Visalakshan.Rahul.pdf
PB  - Oregon Health and Science University
LA  - eng
PY  - 2023-09-12
ID  - 41886
L4  - https://digitalcollections.ohsu.edu/record/41886/files/ResearchWeek.2023.Visalakshan.Rahul.pdf
KW  - Cell Culture Techniques
KW  - Tissue Engineering
KW  - Bioprinting
KW  - Microfluidics
KW  - Biomineralization
KW  - Osteogenesis
KW  - human bone regeneration
KW  - bone defects
KW  - human mesenchymal stem cells
TI  - Faster biomineralization and osteogenesis on-a-chip  using 3D bioprinting and microfluidics
Y1  - 2023-09-12
L2  - https://digitalcollections.ohsu.edu/record/41886/files/ResearchWeek.2023.Visalakshan.Rahul.pdf
LK  - https://digitalcollections.ohsu.edu/record/41886/files/ResearchWeek.2023.Visalakshan.Rahul.pdf
UR  - https://digitalcollections.ohsu.edu/record/41886/files/ResearchWeek.2023.Visalakshan.Rahul.pdf
ER  -