@article{ETD,
      school = {Ph.D.},
      author = {Weeder, Benjamin},
      url = {http://digitalcollections.ohsu.edu/record/42312},
      title = {Dynamics of antigen processing and presentation in the  context of cancer},
      publisher = {Oregon Health and Science University},
      abstract = {Immunotherapeutic approaches, aimed at modulating the  immune system’s response to cancer and other diseases,  have garnered increasing attention over the past decade.  For some cancers such as melanoma, non-small cell lung  cancer, and B-cell lymphomas, immunotherapy options have  been transformative and some patients respond even in the  most aggressive and refractory cases. Despite the optimism  surrounding various immune-based approaches, many patients  still don’t respond to treatment and the reasons why are  poorly understood. The disparity in responses across  patients and cancer types has highlighted a dire need for a  better mechanistic understanding of the factors involved in  therapeutic response to immunotherapies; supported by tools  that help define which patients will benefit from these  novel treatment options. While a variety of approaches  exist in the immunotherapy space, some with systemic  affects and others focused on specific immune targets, all  approaches rely heavily on the adaptive immune system and  response to class I antigens.},
      number = {ETD},
      doi = {https://doi.org/10.6083/bpxhc42312},
      recid = {42312},
      address = {2023-11-07},
}