TY - GEN N2 - Prostate disease is ubiquitous in aging men. Prostate disease includes BPH, PC, and prostatitis, and these diseases share many symptoms such as lower urinary tract symptoms (LUTS) and blood in urine. There have been efforts to develop better prostate disease tests, including interrogating the composition of bacteria in urine and in blood. In this dissertation, we evaluated the urinary microbiome and its relationships with LUTS and prostate disease in a large cohort of men, evaluated microbial DNA in fractions of blood of men with PC, and benchmarked microbiome analysis methods. DO - 10.6083/bpxhc42381 DO - doi AB - Prostate disease is ubiquitous in aging men. Prostate disease includes BPH, PC, and prostatitis, and these diseases share many symptoms such as lower urinary tract symptoms (LUTS) and blood in urine. There have been efforts to develop better prostate disease tests, including interrogating the composition of bacteria in urine and in blood. In this dissertation, we evaluated the urinary microbiome and its relationships with LUTS and prostate disease in a large cohort of men, evaluated microbial DNA in fractions of blood of men with PC, and benchmarked microbiome analysis methods. AD - Oregon Health and Science University T1 - Investigating the human microbiome in prostate health and disease: examining low microbial biomass human samples ED - Karstens, Lisa ED - PI DA - 2023-11-24 AU - Bowie, Kate L1 - https://digitalcollections.ohsu.edu/record/42381/files/Bowie.Kate.2023.pdf PB - Oregon Health and Science University LA - eng PY - 2023-11-24 ID - 42381 L4 - https://digitalcollections.ohsu.edu/record/42381/files/Bowie.Kate.2023.pdf KW - Prostate KW - Microbiota KW - Mycobiome KW - Prostate KW - 16s rrna gene sequencing TI - Investigating the human microbiome in prostate health and disease: examining low microbial biomass human samples Y1 - 2023-11-24 L2 - https://digitalcollections.ohsu.edu/record/42381/files/Bowie.Kate.2023.pdf LK - https://digitalcollections.ohsu.edu/record/42381/files/Bowie.Kate.2023.pdf UR - https://digitalcollections.ohsu.edu/record/42381/files/Bowie.Kate.2023.pdf ER -