000042381 001__ 42381
000042381 005__ 20240124114341.0
000042381 0247_ $$2doi$$a10.6083/bpxhc42381
000042381 037__ $$aETD
000042381 041__ $$aeng
000042381 245__ $$aInvestigating the human microbiome in prostate health and disease: examining low microbial biomass human samples
000042381 260__ $$bOregon Health and Science University
000042381 269__ $$a2023-11-24
000042381 336__ $$aDissertation
000042381 502__ $$bPh.D.
000042381 502__ $$gBiomedical Engineering
000042381 520__ $$aProstate disease is ubiquitous in aging men. Prostate disease includes BPH, PC, and prostatitis, and these diseases share many symptoms such as lower urinary tract symptoms (LUTS) and blood in urine. There have been efforts to develop better prostate disease tests, including interrogating the composition of bacteria in urine and in blood. In this dissertation, we evaluated the urinary microbiome and its relationships with LUTS and prostate disease in a large cohort of men, evaluated microbial DNA in fractions of blood of men with PC, and benchmarked microbiome analysis methods.
000042381 540__ $$fCC BY
000042381 542__ $$fIn copyright - other owner
000042381 650__ $$aProstate$$024727
000042381 650__ $$aMicrobiota$$040384
000042381 650__ $$aMycobiome$$012092
000042381 650__ $$aProstate$$024727
000042381 651__ $$aOregon$$041094
000042381 6531_ $$a16s rrna gene sequencing
000042381 691__ $$aSchool of Medicine$$041369
000042381 692__ $$aDepartment of Biomedical Engineering$$041397
000042381 7001_ $$aBowie, Kate$$uOregon Health and Science University$$041354$$10000-0001-6113-5441
000042381 7201_ $$aKarstens, Lisa$$uOregon Health and Science University$$041354$$ePI$$7Personal
000042381 8564_ $$91db25a46-5b60-4e9f-b501-ceb3f9ffd9ff$$s22629639$$uhttps://digitalcollections.ohsu.edu/record/42381/files/Bowie.Kate.2023.pdf
000042381 909CO $$ooai:digitalcollections.ohsu.edu:42381$$pstudent-work
000042381 980__ $$aTheses and Dissertations
000042381 981__ $$aPublished$$b2023-12-15