000042683 001__ 42683
000042683 005__ 20240208123139.0
000042683 0247_ $$2doi$$a10.6083/bpxhc42683
000042683 037__ $$aETD
000042683 041__ $$aeng
000042683 245__ $$aRetinoic acid inducible gene-I (RIG-I) modulates endothelial cell function
000042683 260__ $$bOregon Health and Science University
000042683 269__ $$a2024-02-07
000042683 336__ $$aDissertation
000042683 502__ $$bPh.D.
000042683 502__ $$gCancer Biology
000042683 520__ $$aThis thesis describes the role of RI-I modulation in the vascular system. I identify a novel role for RIG-I activation in endothelial function, as well as a role for RIG-I inhibition in endothelial function. Together, I find that homeostatic RIG-I signaling is critical for proper endothelial activity.
000042683 540__ $$fCC BY
000042683 542__ $$fIn copyright - single owner
000042683 650__ $$aEndothelial Cells$$035222
000042683 650__ $$aVascular Endothelial Growth Factor Receptor-2$$035028
000042683 650__ $$aInflammation$$020800
000042683 6531_ $$ainnate immune system
000042683 6531_ $$aRIG-I
000042683 6531_ $$aangiogenesis
000042683 691__ $$aSchool of Medicine$$041369
000042683 692__ $$aDepartment of Cell, Developmental and Cancer Biology$$041399
000042683 7001_ $$aBaris, Adrian$$uOregon Health and Science University$$041354$$10000-0002-4091-9711
000042683 7201_ $$aAnand, Sudarshan$$uOregon Health and Science University$$041354$$ePI$$7Personal
000042683 8564_ $$91e8438e8-b413-44f0-93a7-4b7ad1658d9a$$s8744603$$uhttps://digitalcollections.ohsu.edu/record/42683/files/Baris.Adrian.2024.pdf
000042683 909CO $$ooai:digitalcollections.ohsu.edu:42683$$pstudent-work
000042683 980__ $$aTheses and Dissertations
000042683 981__ $$aPublished$$b2024-02-07