@article{ETD,
      recid = {42699},
      author = {Flynn, Patrick},
      title = {Bloodlines matter: leukemia associated mutation FLT3-ITD  disrupts dendritic cell homeostasis and leads to altered T  cell phenotypes},
      publisher = {Oregon Health and Science University},
      school = {Ph.D.},
      address = {2024-02-24},
      number = {ETD},
      abstract = {Dendritic cells (DCs) play a crucial role in mediating  immune responses to pathogens and tumors, with their  development influenced by signaling from the FLT3 receptor  tyrosine kinase in bone marrow myeloid progenitors. Recent  updates differentiate between conventional DCs (cDCs) and  plasmacytoid DCs (pDCs). Activating mutations in FLT3, such  as FLT3-ITD, correlate with poor outcomes in acute myeloid  leukemia (AML). Distinguishing cDCs from AML cells can be  challenging due to their shared lineage.},
      url = {http://digitalcollections.ohsu.edu/record/42699},
      doi = {https://doi.org/10.6083/bpxhc42699},
}