TY - GEN AB - The goal of this dissertation is to improve understanding and treatment for the chorioretinopathy seen in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD) patients by examining the molecular mechanisms and testing potential treatments for LCHADD chorioretinopathy using a novel LCHADD mouse model. AD - Oregon Health and Science University AU - Babcock, Shannon DA - 2024-06-13 DO - 10.6083/bpxhc43378 DO - doi ED - Gillingham, Melanie ED - PI ID - 43378 KW - Mitochondrial Trifunctional Protein KW - Genetic Therapy KW - Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase KW - Retinal Pigment Epithelium KW - LCHADD KW - chorioretinopathy KW - gene addition KW - fatty acid oxidation KW - RPE L1 - https://digitalcollections.ohsu.edu/record/43378/files/Babcock.Shannon.2024.pdf L2 - https://digitalcollections.ohsu.edu/record/43378/files/Babcock.Shannon.2024.pdf L4 - https://digitalcollections.ohsu.edu/record/43378/files/Babcock.Shannon.2024.pdf LA - eng LK - https://digitalcollections.ohsu.edu/record/43378/files/Babcock.Shannon.2024.pdf N2 - The goal of this dissertation is to improve understanding and treatment for the chorioretinopathy seen in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD) patients by examining the molecular mechanisms and testing potential treatments for LCHADD chorioretinopathy using a novel LCHADD mouse model. PB - Oregon Health and Science University PY - 2024-06-13 T1 - Studying LCHADD chorioretinopathy using a novel LCHADD mouse model TI - Studying LCHADD chorioretinopathy using a novel LCHADD mouse model UR - https://digitalcollections.ohsu.edu/record/43378/files/Babcock.Shannon.2024.pdf Y1 - 2024-06-13 ER -