TY - THES AB - The aim of this research is to utilize MRF techniques to characterize vascularization differences between healthy pancreas tissue and tumorous tissue. To do this, both healthy volunteers and cancer patients eligible for surgery were scanned using contrast generated by iron nanoparticles (Ferumoxytol), and values for T1, T2 and T2* were extracted from a dictionary fitting. A secondary aim of this project was to analyze the differences between breath hold and free breathing techniques in MRF scans, thus scans were completed with both breath holds and free breathing. AD - Oregon Health and Science University AU - Barton, Zachary J. DA - 2024-06-07 DO - 10.6083/bpxhc43379 DO - doi ED - Wyatt, Cory R. ED - Guimaraes, Alexander R. ED - Chang, Young Hwan ED - Mench, M. Anna ED - Mentor ED - Co-Mentor ED - Committee member ED - Committee chair ID - 43379 KW - Magnetic Resonance Imaging KW - Pancreatic Neoplasms KW - MRI KW - pancreatic cancer KW - fingerprinting KW - ferumoxytol KW - feraheme L1 - https://digitalcollections.ohsu.edu/record/43379/files/Bushberg%20Printable%20License.pdf L1 - https://digitalcollections.ohsu.edu/record/43379/files/Barton.Zachary.2024.pdf L2 - https://digitalcollections.ohsu.edu/record/43379/files/Bushberg%20Printable%20License.pdf L2 - https://digitalcollections.ohsu.edu/record/43379/files/Barton.Zachary.2024.pdf L4 - https://digitalcollections.ohsu.edu/record/43379/files/Bushberg%20Printable%20License.pdf L4 - https://digitalcollections.ohsu.edu/record/43379/files/Barton.Zachary.2024.pdf LA - eng LK - https://digitalcollections.ohsu.edu/record/43379/files/Bushberg%20Printable%20License.pdf LK - https://digitalcollections.ohsu.edu/record/43379/files/Barton.Zachary.2024.pdf N2 - The aim of this research is to utilize MRF techniques to characterize vascularization differences between healthy pancreas tissue and tumorous tissue. To do this, both healthy volunteers and cancer patients eligible for surgery were scanned using contrast generated by iron nanoparticles (Ferumoxytol), and values for T1, T2 and T2* were extracted from a dictionary fitting. A secondary aim of this project was to analyze the differences between breath hold and free breathing techniques in MRF scans, thus scans were completed with both breath holds and free breathing. PB - Oregon Health and Science University PY - 2024-06-07 T1 - Multi-parametric MRI fingerprinting analysis of pancreatic lesions with ferumoxytol contrast for correlation with vascular structure TI - Multi-parametric MRI fingerprinting analysis of pancreatic lesions with ferumoxytol contrast for correlation with vascular structure UR - https://digitalcollections.ohsu.edu/record/43379/files/Bushberg%20Printable%20License.pdf UR - https://digitalcollections.ohsu.edu/record/43379/files/Barton.Zachary.2024.pdf Y1 - 2024-06-07 ER -