TY - GEN AB - In people with Parkinson's disease (PD), walking impairments like reduced stability, speed, and stride length are common. These impairments involve a shift from automatic to compensatory control, mainly in the prefrontal cortex (PFC). Increased gait variability, seen in PD, suggests reduced automaticity and higher PFC activity, indicating greater attentional demand. However, it's unclear if specific gait domains correlate with changes in PFC activity. We hypothesize that increased PFC activity during walking may correspond to higher gait variability. AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AU - Ragothaman, Anjanibhargavi AU - Liu, William AU - Silva-Batista, Carla AU - Carlson-Kuhta, Patricia AU - Harker, Graham AU - Ellison, Jacqueline AU - Horak, Fay B. AU - Mancini, Martina DA - 2024 DO - 10.6083/bpxhc43560 DO - doi ID - 43560 KW - Parkinson Disease KW - Walking KW - Gait L1 - https://digitalcollections.ohsu.edu/record/43560/files/ResearchWeek.2024.Ragothaman.Anjanibhargavi.pdf L2 - https://digitalcollections.ohsu.edu/record/43560/files/ResearchWeek.2024.Ragothaman.Anjanibhargavi.pdf L4 - https://digitalcollections.ohsu.edu/record/43560/files/ResearchWeek.2024.Ragothaman.Anjanibhargavi.pdf LA - eng LK - https://digitalcollections.ohsu.edu/record/43560/files/ResearchWeek.2024.Ragothaman.Anjanibhargavi.pdf N2 - In people with Parkinson's disease (PD), walking impairments like reduced stability, speed, and stride length are common. These impairments involve a shift from automatic to compensatory control, mainly in the prefrontal cortex (PFC). Increased gait variability, seen in PD, suggests reduced automaticity and higher PFC activity, indicating greater attentional demand. However, it's unclear if specific gait domains correlate with changes in PFC activity. We hypothesize that increased PFC activity during walking may correspond to higher gait variability. PB - Oregon Health and Science University PY - 2024 T1 - Association between pre-frontal cortex activity and gait domains in people with Parkinson's disease TI - Association between pre-frontal cortex activity and gait domains in people with Parkinson's disease UR - https://digitalcollections.ohsu.edu/record/43560/files/ResearchWeek.2024.Ragothaman.Anjanibhargavi.pdf Y1 - 2024 ER -