000043560 001__ 43560
000043560 005__ 20240823152913.0
000043560 0247_ $$2doi$$a10.6083/bpxhc43560
000043560 037__ $$aIR
000043560 041__ $$aeng
000043560 245__ $$aAssociation between pre-frontal cortex activity and gait domains in people with Parkinson's disease
000043560 260__ $$bOregon Health and Science University
000043560 269__ $$a2024
000043560 336__ $$aAbstract
000043560 520__ $$aIn people with Parkinson's disease (PD), walking impairments like reduced stability, speed, and stride length are common. These impairments involve a shift from automatic to compensatory control, mainly in the prefrontal cortex (PFC). Increased gait variability, seen in PD, suggests reduced automaticity and higher PFC activity, indicating greater attentional demand. However, it's unclear if specific gait domains correlate with changes in PFC activity. We hypothesize that increased PFC activity during walking may correspond to higher gait variability.
000043560 540__ $$fCC BY
000043560 542__ $$fIn copyright - joint owners
000043560 650__ $$aParkinson Disease$$023617
000043560 650__ $$aWalking$$028911
000043560 650__ $$aGait$$019340
000043560 691__ $$aSchool of Medicine$$041369
000043560 692__ $$aDepartment of Neurology$$041431
000043560 7001_ $$aRagothaman, Anjanibhargavi$$uOregon Health and Science University$$041354
000043560 7001_ $$aLiu, William$$uOregon Health and Science University$$041354
000043560 7001_ $$aSilva-Batista, Carla$$uOregon Health and Science University$$041354
000043560 7001_ $$aCarlson-Kuhta, Patricia$$uOregon Health and Science University$$041354
000043560 7001_ $$aHarker, Graham$$uOregon Health and Science University$$041354
000043560 7001_ $$aEllison, Jacqueline$$uOregon Health and Science University$$041354
000043560 7001_ $$aHorak, Fay B.$$uOregon Health and Science University$$041354
000043560 7001_ $$aMancini, Martina$$uOregon Health and Science University$$041354
000043560 711__ $$aResearch Week$$uOregon Health and Science University$$d2024
000043560 8564_ $$9294a59ac-4328-4ce2-b675-0cdb95f05cb4$$s111731$$uhttps://digitalcollections.ohsu.edu/record/43560/files/ResearchWeek.2024.Ragothaman.Anjanibhargavi.pdf
000043560 980__ $$aResearch Week