@article{IR,
      recid = {43562},
      author = {Maior-Leichtfried, Anna and Blomenkamp, Hannah and Dean,  Tyler and Kirigiti, Melissa and Sauter, Kristin and Kievit,  Paul},
      title = {Effects of diet changes and maternal metformin consumption  during pregnancy on both maternal and offspring insulin  resistance},
      publisher = {Oregon Health and Science University},
      address = {2024},
      number = {IR},
      abstract = {Pregnancy causes complex hormonal changes, leading to  physiologic decreases of insulin sensitivity, onset of  gestational diabetes (GDM), and worsening conditions  associated with insulin resistance (IR). These factors,  although not fully understood, are closely linked to the  metabolic effects of elevated hormones during pregnancy.  Studies suggest GDM can cause offspring to develop impaired  glucose tolerance. Metformin reduces hepatic glucose  production, increases hepatic insulin sensitivity, and  combats GDM/IR conditions. It is unknown how metformin  exposure during fetal development impacts glucose  homeostasis in offspring.},
      url = {http://digitalcollections.ohsu.edu/record/43562},
      doi = {https://doi.org/10.6083/bpxhc43562},
}