TY - GEN AB - The theory that, in positively charged molecules, longer side chains act as a lancet leading to bacterial disruption remains unproved. Given the flexibility and size of the chain compared with the thickness of the bacterial cell wall, the aim of this study was to elucidate the mechanism through which the combination of chain-length and charge in QAM-containing materials affects biofilm inhibition. AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AU - Wong, Jade AU - Lucena, FS AU - Logan, M AU - Lewis, SH AU - Pfeifer, CS DA - 2024 DO - 10.6083/bpxhc43611 DO - doi ID - 43611 KW - Biofilms KW - Anti-Bacterial Agents KW - Anti-Infective Agents KW - Ammonium Compounds KW - Methacrylates KW - quaternary ammonium methacrylate KW - antimicrobial KW - bactericidal mechanism L1 - https://digitalcollections.ohsu.edu/record/43611/files/ResearchWeek.2024.Wong.Jade.pdf L2 - https://digitalcollections.ohsu.edu/record/43611/files/ResearchWeek.2024.Wong.Jade.pdf L4 - https://digitalcollections.ohsu.edu/record/43611/files/ResearchWeek.2024.Wong.Jade.pdf LA - eng LK - https://digitalcollections.ohsu.edu/record/43611/files/ResearchWeek.2024.Wong.Jade.pdf N2 - The theory that, in positively charged molecules, longer side chains act as a lancet leading to bacterial disruption remains unproved. Given the flexibility and size of the chain compared with the thickness of the bacterial cell wall, the aim of this study was to elucidate the mechanism through which the combination of chain-length and charge in QAM-containing materials affects biofilm inhibition. PB - Oregon Health and Science University PY - 2024 T1 - Mechanistic study of the antibiofilm effect of QAM-based materials TI - Mechanistic study of the antibiofilm effect of QAM-based materials UR - https://digitalcollections.ohsu.edu/record/43611/files/ResearchWeek.2024.Wong.Jade.pdf Y1 - 2024 ER -