000043611 001__ 43611 000043611 005__ 20240823112127.0 000043611 0247_ $$2doi$$a10.6083/bpxhc43611 000043611 037__ $$aIR 000043611 041__ $$aeng 000043611 245__ $$aMechanistic study of the antibiofilm effect of QAM-based materials 000043611 260__ $$bOregon Health and Science University 000043611 269__ $$a2024 000043611 336__ $$aAbstract 000043611 520__ $$aThe theory that, in positively charged molecules, longer side chains act as a lancet leading to bacterial disruption remains unproved. Given the flexibility and size of the chain compared with the thickness of the bacterial cell wall, the aim of this study was to elucidate the mechanism through which the combination of chain-length and charge in QAM-containing materials affects biofilm inhibition. 000043611 540__ $$fCC BY 000043611 542__ $$fIn copyright - joint owners 000043611 650__ $$aBiofilms$$030801 000043611 650__ $$aAnti-Bacterial Agents$$014846 000043611 650__ $$aAnti-Infective Agents$$014838 000043611 650__ $$aAmmonium Compounds$$040488 000043611 650__ $$aMethacrylates$$022130 000043611 6531_ $$aquaternary ammonium methacrylate 000043611 6531_ $$aantimicrobial 000043611 6531_ $$abactericidal mechanism 000043611 691__ $$aSchool of Dentistry$$041368 000043611 692__ $$aDivision of Biomaterials and Biomechanics$$041456 000043611 7001_ $$aWong, Jade$$uOregon Health and Science University$$041354 000043611 7001_ $$aLucena, FS$$uOregon Health and Science University$$041354 000043611 7001_ $$aLogan, M$$uOregon Health and Science University$$041354 000043611 7001_ $$aLewis, SH$$uOregon Health and Science University$$041354 000043611 7001_ $$aPfeifer, CS$$uOregon Health and Science University$$041354 000043611 711__ $$aResearch Week$$uOregon Health and Science University$$d2024 000043611 8564_ $$926e96689-91c6-44fa-8351-4457b8bd1c2a$$s211914$$uhttps://digitalcollections.ohsu.edu/record/43611/files/ResearchWeek.2024.Wong.Jade.pdf 000043611 980__ $$aResearch Week