000043627 001__ 43627 000043627 005__ 20240822151426.0 000043627 0247_ $$2doi$$a10.6083/bpxhc43627 000043627 037__ $$aIR 000043627 041__ $$aeng 000043627 245__ $$aA systematic comparison of propensity score matching and structural causal models for clinical applications 000043627 260__ $$bOregon Health and Science University 000043627 269__ $$a2024 000043627 336__ $$aAbstract 000043627 520__ $$aCausal inference methods play a vital role in health sciences research, requiring robust methodologies for treatment evaluation and clinical decision-making. Propensity Score Matching (PSM) and Structural Causal Models (SCMs) are key approaches, both grounded in the potential outcome framework but differing in their foundations — PSM follows Rubin's Causal Model, while SCMs follows the Structural Theory of Causation. Despite their shared objectives, these methods diverge significantly in methodologies and interpretations. We systematically study the methods with a specific clinical application. 000043627 540__ $$fCC BY 000043627 542__ $$fIn copyright - joint owners 000043627 650__ $$aPropensity Score$$038905 000043627 650__ $$aCausality$$028793 000043627 650__ $$aAcute Kidney Injury$$039113 000043627 6531_ $$apropensity score matching 000043627 6531_ $$astructural causal modeling 000043627 6531_ $$astructural theory of causation 000043627 692__ $$aOregon Clinical and Translational Research Institute$$041494 000043627 7001_ $$aKhellah, Layaal$$uOregon Health and Science University$$041354 000043627 7001_ $$aNaved, Mobasshir A.$$uOregon Health and Science University$$041354 000043627 7001_ $$aAdib, Riddhiman$$uOregon Health and Science University$$041354 000043627 7001_ $$aPatidar, Kavish$$uOregon Health and Science University$$041354 000043627 7001_ $$aAdibuzzaman, Mohammad$$uOregon Health and Science University$$041354 000043627 711__ $$aResearch Week$$uOregon Health and Science University$$d2024 000043627 8564_ $$9de80739a-c12a-4ad6-b3e2-c9802ae06de0$$s141796$$uhttps://digitalcollections.ohsu.edu/record/43627/files/ResearchWeek.2024.Khellah.Layaal.pdf 000043627 980__ $$aResearch Week