TY - GEN AB - Neurocysticercosis (NCC), a central nervous system (CNS) infection with Taenia solium (pork tapeworm), is a leading infectious cause of epilepsy in endemic areas. Treating T. solium taeniasis with anthelminthic medications (AHMs) like niclosamide or praziquantel (PZQ) is essential to prevent NCC. However, co-infections of taeniasis with viable NCC, the presence of living CNS cysts, impose a risk of neurological adverse events with PZQ, complicating treatment decisions. The availability and type of AHMs and lack of feasible diagnostic methods for NCC in community settings is a major challenge in informing anthelminthic treatment decisions, warranting exploration of NCC prevalence among people with taeniasis. This study aimed to describe the prevalence of taeniasis in screened communities and the prevalence of NCC, along with key characteristics, among people with confirmed taeniasis from northern Peru. AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AU - Wardle, Melissa AU - Allen, Samantha E. AU - Bustos, Javier AU - Gamboa, Ricardo AU - Hall, Eric AU - Neiderhausen, Meike AU - Vilchez, Percy AU - Garcia, Hector H. AU - O’Neal, Seth E. DA - 2024 DO - 10.6083/bpxhc43635 DO - doi ID - 43635 KW - Taenia solium KW - Taeniasis KW - Neurocysticercosis KW - Praziquantel KW - Niclosamide KW - Swine KW - Coinfection KW - Communicable Diseases KW - Epilepsy KW - pork tapeworm KW - anthelminthic medications KW - community-based treatment strategies L1 - https://digitalcollections.ohsu.edu/record/43635/files/ResearchWeek.2024.Wardle.Melissa.pdf L2 - https://digitalcollections.ohsu.edu/record/43635/files/ResearchWeek.2024.Wardle.Melissa.pdf L4 - https://digitalcollections.ohsu.edu/record/43635/files/ResearchWeek.2024.Wardle.Melissa.pdf LA - eng LK - https://digitalcollections.ohsu.edu/record/43635/files/ResearchWeek.2024.Wardle.Melissa.pdf N2 - Neurocysticercosis (NCC), a central nervous system (CNS) infection with Taenia solium (pork tapeworm), is a leading infectious cause of epilepsy in endemic areas. Treating T. solium taeniasis with anthelminthic medications (AHMs) like niclosamide or praziquantel (PZQ) is essential to prevent NCC. However, co-infections of taeniasis with viable NCC, the presence of living CNS cysts, impose a risk of neurological adverse events with PZQ, complicating treatment decisions. The availability and type of AHMs and lack of feasible diagnostic methods for NCC in community settings is a major challenge in informing anthelminthic treatment decisions, warranting exploration of NCC prevalence among people with taeniasis. This study aimed to describe the prevalence of taeniasis in screened communities and the prevalence of NCC, along with key characteristics, among people with confirmed taeniasis from northern Peru. PB - Oregon Health and Science University PY - 2024 T1 - Co-occurrence of neurocysticercosis and taeniasis within communities of northern Peru: implications for anthelminthic treatment strategies TI - Co-occurrence of neurocysticercosis and taeniasis within communities of northern Peru: implications for anthelminthic treatment strategies UR - https://digitalcollections.ohsu.edu/record/43635/files/ResearchWeek.2024.Wardle.Melissa.pdf Y1 - 2024 ER -