TY  - GEN
AB  - The use of multimodal analgesia is preferred over single-agent analgesia for postoperative pain management due to synergistic modulations of pain pathways. The two most common first-line analgesics, non-steroidal anti-inflammatory drugs (NSAIDs) and opioids, both have the potential to confound experimental outcomes depending on the research paradigm. If only one of these drug classes is compatible with a particular study design, a different adjunctive analgesic may be necessary to provide sufficient pain management and ensure animal welfare. A retroactive assessment of pain behaviors from the first 30-60 min postoperatively will also be evaluated.
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AU  - Alionhart, Rachael
AU  - Carlson, McKayla
AU  - White, Alina
AU  - Saunders, Kim
AU  - Kopanke, Jennifer
DA  - 2024
DO  - 10.6083/bpxhc43647
DO  - doi
ID  - 43647
KW  - Ketamine
KW  - Rats, Sprague-Dawley
KW  - Grooming
KW  - Rats
KW  - Pain Management
KW  - Pain, Postoperative
KW  - Pain Measurement
KW  - postoperative analgesia
L1  - https://digitalcollections.ohsu.edu/record/43647/files/ResearchWeek.2024.Alionhart.Rachael.pdf
L2  - https://digitalcollections.ohsu.edu/record/43647/files/ResearchWeek.2024.Alionhart.Rachael.pdf
L4  - https://digitalcollections.ohsu.edu/record/43647/files/ResearchWeek.2024.Alionhart.Rachael.pdf
LA  - eng
LK  - https://digitalcollections.ohsu.edu/record/43647/files/ResearchWeek.2024.Alionhart.Rachael.pdf
N2  - The use of multimodal analgesia is preferred over single-agent analgesia for postoperative pain management due to synergistic modulations of pain pathways. The two most common first-line analgesics, non-steroidal anti-inflammatory drugs (NSAIDs) and opioids, both have the potential to confound experimental outcomes depending on the research paradigm. If only one of these drug classes is compatible with a particular study design, a different adjunctive analgesic may be necessary to provide sufficient pain management and ensure animal welfare. A retroactive assessment of pain behaviors from the first 30-60 min postoperatively will also be evaluated.
PB  - Oregon Health and Science University
PY  - 2024
T1  - The effects of subcutaneous ketamine on postoperative analgesia and behavior in female Sprague-Dawley rats
TI  - The effects of subcutaneous ketamine on postoperative analgesia and behavior in female Sprague-Dawley rats
UR  - https://digitalcollections.ohsu.edu/record/43647/files/ResearchWeek.2024.Alionhart.Rachael.pdf
Y1  - 2024
ER  -