@article{IR, recid = {43676}, author = {Abu Hweij, Zaina and Liang, Florence and Zhang, Sophie}, title = {Noninvasive acute compartment syndrome diagnosis using random forest machine learning}, publisher = {Oregon Health and Science University}, address = {2024}, number = {IR}, abstract = {Acute compartment syndrome (ACS) is an orthopedic emergency caused by elevated pressure within a muscle compartment that can lead to permanent tissue damage and death. Current ACS diagnosis relies heavily on patient-reported symptoms, a method that is subjective and often followed by invasive intracompartmental pressure measurements that can be faulty in motion settings. Reliable motion diagnosis is critical for long-term monitoring that involves limb movement. This study proposes an objective and noninvasive diagnostic for ACS. Our device utilizes a random forest machine learning model that uses analog readings from force-sensitive resistors (FSRs) placed on the skin. To validate the machine learning diagnostic model, a data set containing FSR measurements and the corresponding simulated pressure was created for motion and motionless scenarios. Our diagnostic achieved up to 98% accuracy and excelled in key performance metrics, including sensitivity (97%) and specificity (98%), with a statistically insignificant (±5% error bars) performance difference in motion present cases. These results demonstrate the potential of noninvasive ACS diagnostics to meet clinical accuracy standards in real world scenarios.}, url = {http://digitalcollections.ohsu.edu/record/43676}, doi = {https://doi.org/10.6083/bpxhc43676}, }