000043677 001__ 43677
000043677 005__ 20240822075326.0
000043677 0247_ $$2doi$$a10.6083/bpxhc43677
000043677 037__ $$aIR
000043677 041__ $$aeng
000043677 245__ $$aWheel-running decreases binge-like drinking in a genetic mouse model of risk for drinking to intoxication
000043677 260__ $$bOregon Health and Science University
000043677 269__ $$a2024
000043677 336__ $$aAbstract
000043677 520__ $$aMaintaining healthy levels of physical activity (PA) is a noninvasive, clinically proven means of reducing the onset of >40 chronic diseases and may provide a strategy for managing harmful alcohol use. Studies indicate a positive relationship between PA levels and alcohol intake in moderate drinkers, while heavy drinkers tend toward less physical activity. This suggests healthy PA levels may promote moderate alcohol intake and therefore harm reduction. Wheel-running (WR) – a well-characterized rodent model of voluntary PA – is known to reduce self-administration and craving for many drugs of abuse; however, its effects on alcohol intake are mixed.
000043677 536__ $$oNIH Grants$$cU01 AA013519, P60 AA010760, K99 AA030806, T32 AA007468
000043677 536__ $$oU.S. Department of Veterans Affairs Grant$$cI01 BX004699
000043677 536__ $$oGift from the John R. Andrews Family
000043677 540__ $$fCC BY
000043677 542__ $$fIn copyright - joint owners
000043677 650__ $$aExercise$$028419
000043677 650__ $$aSedentary Behavior$$038887
000043677 650__ $$aAlcohol Drinking$$014403
000043677 650__ $$aEthanol$$014406
000043677 650__ $$aAlcoholism$$014412
000043677 650__ $$aChronic Disease$$016715
000043677 6531_ $$aphysical activity
000043677 6531_ $$agenetic animal models
000043677 692__ $$aDepartment of Behavioral Neuroscience$$041394
000043677 7001_ $$aGrigsby, Kolter$$uOregon Health and Science University$$041354
000043677 7001_ $$aUsmani, Zaynah$$uOregon Health and Science University$$041354
000043677 7001_ $$aAnderson, Justin$$uOregon Health and Science University$$041354
000043677 7001_ $$aOzburn, Angela$$uOregon Health and Science University$$041354
000043677 711__ $$aResearch Week$$uOregon Health and Science University$$d2024
000043677 8564_ $$949ea1253-9e9c-4c37-9bf1-286bf0b1d9a6$$s250498$$uhttps://digitalcollections.ohsu.edu/record/43677/files/ResearchWeek.2024.Grigsby.Kolter.pdf
000043677 980__ $$aResearch Week