@article{ETD,
      recid = {43708},
      author = {Weinstein, Jules B.},
      title = {Antiviral antibodies: interrogating SARS-CoV-2 replication  with antibodies and VHHs},
      publisher = {Oregon Health and Science University},
      school = {Ph.D.},
      address = {2024-09-18},
      number = {ETD},
      abstract = {In this dissertation I explore applications of antibodies  and alpaca-derived antibody fragments, known as VHHs, to  understand severe acute respiratory associated coronavirus  (SARS-CoV-2) biology and develop potential therapeutics  against COVID-19. Here I study pre-existing SARS-CoV-1  antibodies for cross-reactivity with SARS-CoV-2 and design  novel VHHs targeting the viral spike protein (S) and  nucleocapsid protein (N). This work significantly advances  our understanding of SARS-CoV-2 biology, highlighting the  potential for antibody-based therapies and diagnostics  against COVID-19 while also emphasizing the role antibodies  can have in researching a newly emergent disease.},
      url = {http://digitalcollections.ohsu.edu/record/43708},
      doi = {https://doi.org/10.6083/bpxhc43708},
}