TY - GEN N2 - Here we evaluated the accuracy of several freely available software packages to correct for variable gene copy numbers in microbiome profiling using the 16S rRNA gene. We then applied these corrections to a published urinary microbiome dataset to show that the use of one of these packages has a measurable effect on the final results of human urinary microbiome studies. DO - 10.6083/bpxhc43710 DO - doi AB - Here we evaluated the accuracy of several freely available software packages to correct for variable gene copy numbers in microbiome profiling using the 16S rRNA gene. We then applied these corrections to a published urinary microbiome dataset to show that the use of one of these packages has a measurable effect on the final results of human urinary microbiome studies. AD - Oregon Health and Science University AD - Oregon Health and Science University T1 - Evaluation of currently available 16S rRNA gene copy number correction software packages for accuracy and impact in a mock microbial community and urinary microbiome dataset DA - 2024-06-21 AU - Shah, Rebecca AU - Karstens, Lisa L1 - https://digitalcollections.ohsu.edu/record/43710/files/Shah.Karstens.2024.pdf PB - Oregon Health and Science University LA - eng PY - 2024-06-21 ID - 43710 L4 - https://digitalcollections.ohsu.edu/record/43710/files/Shah.Karstens.2024.pdf KW - RNA, Ribosomal, 16S KW - Genes, rRNA KW - Microbiota KW - microbiome profiling KW - 16S rRNA KW - gene copy number correction TI - Evaluation of currently available 16S rRNA gene copy number correction software packages for accuracy and impact in a mock microbial community and urinary microbiome dataset Y1 - 2024-06-21 L2 - https://digitalcollections.ohsu.edu/record/43710/files/Shah.Karstens.2024.pdf LK - https://digitalcollections.ohsu.edu/record/43710/files/Shah.Karstens.2024.pdf UR - https://digitalcollections.ohsu.edu/record/43710/files/Shah.Karstens.2024.pdf ER -