TY  - GEN
AB  - This dissertation showcases three independent studies that address various unknown aspects of a paraneoplastic syndrome called melanoma-associated retinopathy (MAR). Through the analysis of a MAR patient's disease evolution and the development and implementation of a novel bioassay, this text contributes substantially to our understanding of MAR pathology. These clinical findings may shape future MAR diagnosis and treatment, and the mechanism discoveries may guide strategies for therapeutic intervention or disease prevention. 
AD  - Oregon Health and Science University
AU  - Mosavi-Hecht, Ryan
DA  - 2024-11-12
DO  - 10.6083/bpxhc44106
DO  - doi
ED  - Morgans, Catherine
ED  - Duvoisin, Robert
ED  - Saugstad, Julie
ED  - Yang, Paul
ED  - Heyer, Barrett
ED  - Rosenberg, Christopher
ED  - White, Elizabeth
ED  - Berry, Elizabeth
ED  - Shi, Qing
ED  - Garrett, Tavita
ED  - Sivyer, Benjamin
ED  - Haley, Tammie
ED  - Ren, Gaoying
ED  - Carroll, James
ED  - Aicher, Sue
ED  - Mentor
ED  - Co-Mentor
ED  - Committee chair
ED  - Committee member
ED  - Other
ED  - Collaborator
ED  - Collaborator
ED  - Committee member
ED  - Collaborator
ED  - Collaborator
ED  - Collaborator
ED  - Collaborator
ED  - Collaborator
ED  - Collaborator
ED  - Collaborator
ID  - 44106
KW  - Paraneoplastic Syndromes, Ocular
KW  - Blood-Retinal Barrier
KW  - Retinal Neurons
KW  - Endocytosis
KW  - Autoantibodies
KW  - Melanoma
KW  - Retinal Bipolar Cells
KW  - Retina
KW  - Autoimmunity
KW  - melanoma-associated retinopathy
L1  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Wiley_License.pdf
L1  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan.2024.pdf
L1  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Additional_File%281%29.pdf
L1  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Additional_File%282%29.pdf
L2  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Wiley_License.pdf
L2  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan.2024.pdf
L2  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Additional_File%281%29.pdf
L2  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Additional_File%282%29.pdf
L4  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Wiley_License.pdf
L4  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan.2024.pdf
L4  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Additional_File%281%29.pdf
L4  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Additional_File%282%29.pdf
LA  - eng
LK  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Wiley_License.pdf
LK  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan.2024.pdf
LK  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Additional_File%281%29.pdf
LK  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Additional_File%282%29.pdf
N2  - This dissertation showcases three independent studies that address various unknown aspects of a paraneoplastic syndrome called melanoma-associated retinopathy (MAR). Through the analysis of a MAR patient's disease evolution and the development and implementation of a novel bioassay, this text contributes substantially to our understanding of MAR pathology. These clinical findings may shape future MAR diagnosis and treatment, and the mechanism discoveries may guide strategies for therapeutic intervention or disease prevention. 
PB  - Oregon Health and Science University
PY  - 2024-11-12
T1  - Insight into the cellular and molecular mechanisms of melanoma-associated retinopathy
TI  - Insight into the cellular and molecular mechanisms of melanoma-associated retinopathy
UR  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Wiley_License.pdf
UR  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan.2024.pdf
UR  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Additional_File%281%29.pdf
UR  - https://digitalcollections.ohsu.edu/record/44106/files/MosaviHecht.Ryan_Additional_File%282%29.pdf
Y1  - 2024-11-12
ER  -