This study identified key care gaps and early clinical warning signs among patients with hospital-onset sepsis who experienced mortality, with the majority of cases demonstrating potential preventability. Delays in early recognition and antibiotic administration were the most critical and actionable gaps, while other aspects of care, such as antibiotic selection and repeat lactate measurement, were relatively well supported. These findings highlight the need to “think sepsis” earlier and prioritize rapid initiation of treatment to reduce preventable mortality.
