000000458 001__ 458
000000458 005__ 20260303134512.0
000000458 0247_ $$2DOI$$a10.6083/M4PC30BF
000000458 037__ $$aETD
000000458 245__ $$aSerum albumin in relation to change in muscle mass, muscle strength, and muscle power
000000458 260__ $$bOregon Health and Science University
000000458 269__ $$a2009
000000458 336__ $$aThesis
000000458 502__ $$bM.P.H.
000000458 520__ $$aSerum albumin, the most abundant protein in human plasma, transports hormones such as aldosterone, thyroid hormones and androgens and decreases during inflammatory states. Cytokines including IL‑6, TNF‑α, and CRP reduce circulating albumin levels, which can fall sharply after major illness or more subtly with chronic low‑grade inflammation. Low serum albumin is linked to higher risks of cardiovascular disease, disability and mortality. Sarcopenia, the age‑related loss of muscle mass and strength, is common in older adults and contributes to frailty, falls and loss of independence. This study explores the relationship between inflammation‑related reductions in serum albumin and the development of sarcopenia, highlighting albumin as a potential biomarker for muscle decline and adverse health outcomes in aging.
000000458 540__ $$fCC BY
000000458 542__ $$fIn copyright - single owner
000000458 650__ $$aSerum Albumin$$025899
000000458 650__ $$aMuscle Strength$$037485
000000458 650__ $$aAging$$014358
000000458 650__ $$aMuscle, Skeletal$$030835
000000458 691__ $$aSchool of Medicine$$041369
000000458 692__ $$aDepartment of Public Health and Preventive Medicine$$041444
000000458 7001_ $$aSnyder, Caryn$$uOregon Health and Science University$$041354
000000458 7201_ $$aMarshall, Lynn$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor
000000458 8564_ $$95ca4ba93-759b-4c3a-a9f6-d47314968fb6$$s1684384$$uhttps://digitalcollections.ohsu.edu/record/458/files/459_etd.pdf$$ePublic$$2db9a0c7127741b540f836d0c3a3db7df$$31
000000458 905__ $$a/rest/prod/d7/91/sg/18/d791sg188
000000458 909CO $$ooai:digitalcollections.ohsu.edu:458$$pstudent-work
000000458 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument
000000458 980__ $$aTheses and Dissertations