000000460 001__ 460
000000460 005__ 20260203153808.0
000000460 0247_ $$2DOI$$a10.6083/M4DZ069Q
000000460 037__ $$aETD
000000460 245__ $$aCost and utilization of extended release naltrexone for alcohol use disorders
000000460 260__ $$bOregon Health and Science University
000000460 269__ $$a2010
000000460 336__ $$aThesis
000000460 502__ $$bM.P.H.
000000460 520__ $$aThis study compared treatment persistence, health care utilization, and costs among Aetna beneficiaries receiving extended‑release naltrexone (XR‑NTX) for alcohol use disorders (AUDs) with those receiving disulfiram, oral naltrexone, acamprosate, or psychosocial therapy only. Claims data from 2007–2008 included 211 XR‑NTX users and over 11,000 comparison patients. Survival analysis showed greater treatment persistence with XR‑NTX than with oral NTX, acamprosate, or disulfiram. Across groups, outpatient behavioral health visits increased during treatment. However, XR‑NTX patients demonstrated larger reductions in non‑pharmacy health care costs and inpatient and emergency service use, particularly among those with physical or mental health comorbidities. Findings suggest XR‑NTX improves treatment continuity and reduces overall health care utilization relative to alternative therapies.
000000460 540__ $$fCC BY
000000460 542__ $$fIn copyright - single owner
000000460 650__ $$aAlcohol-Related Disorders$$032034
000000460 650__ $$aAlcoholism$$014412
000000460 650__ $$aSubstance-Related Disorders$$032029
000000460 650__ $$aNaltrexone$$022668
000000460 650__ $$aHealth Care Costs$$029646
000000460 691__ $$aSchool of Medicine$$041369
000000460 692__ $$aDepartment of Public Health and Preventive Medicine$$041444
000000460 7001_ $$aBryson, William$$uOregon Health and Science University$$041354
000000460 8564_ $$996662ed0-c97a-4966-9f03-2a6d924e3fbe$$s566827$$uhttps://digitalcollections.ohsu.edu/record/460/files/461_etd.pdf$$ePublic$$2cef424485aba211a762ff6c8ea48c3f3$$31
000000460 905__ $$a/rest/prod/6q/18/2k/14/6q182k142
000000460 909CO $$ooai:digitalcollections.ohsu.edu:460$$pstudent-work
000000460 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument
000000460 980__ $$aTheses and Dissertations