000000462 001__ 462 000000462 005__ 20260220081617.0 000000462 0247_ $$2DOI$$a10.6083/M45D8PTK 000000462 037__ $$aETD 000000462 245__ $$aOvarian steroid regulation of the midbrain corticotropin releasing factor and urocortin systems in macaques 000000462 260__ $$bOregon Health and Science University 000000462 269__ $$a2010 000000462 336__ $$aDissertation 000000462 502__ $$bPh.D. 000000462 502__ $$gNeuroscience 000000462 520__ $$aA significant number of postmenopausal women report increased anxiety and vulnerability to stress, which has been linked to decreased secretion of ovarian steroids. Communication between the serotonin system and the CRF system determines stress sensitivity or resilience. This study examines the effects of the ovarian steroids, estradiol (E) and progesterone (P) on the CRF system components that impact serotonin neurons in the midbrain of nonhuman primates. 000000462 540__ $$fCC BY 000000462 542__ $$fIn copyright - single owner 000000462 650__ $$aNeuroendocrinology$$022837 000000462 650__ $$aMenopause$$022037 000000462 650__ $$aUrocortins$$038066 000000462 650__ $$aEstrogens$$018663 000000462 650__ $$aMacaca mulatta$$021724 000000462 650__ $$aAnxiety$$014946 000000462 650__ $$aHormone Replacement Therapy$$032264 000000462 650__ $$aCorticotropin-Releasing Hormone$$017131 000000462 650__ $$aStress, Physiological$$026467 000000462 650__ $$aEstrogen Replacement Therapy$$028742 000000462 650__ $$aCorticotropin-Releasing Hormone$$017131 000000462 6531_ $$arhesus monkey 000000462 691__ $$aSchool of Medicine$$041369 000000462 692__ $$aVollum Institute$$041509 000000462 7001_ $$aSanchez Thwing, Rachel$$uOregon Health and Science University$$041354 000000462 7201_ $$aBethea, Cynthia$$uOregon Health and Science University$$041354$$7Personal$$eMentor 000000462 8564_ $$99c1dc51e-21a0-4e69-8d3a-c23c1531fccf$$s3473610$$uhttps://digitalcollections.ohsu.edu/record/462/files/463_etd.pdf$$ePublic$$25935af687dae8854c4c73fc897971e6d$$31 000000462 905__ $$a/rest/prod/2n/49/t1/71/2n49t171b 000000462 909CO $$ooai:digitalcollections.ohsu.edu:462$$pstudent-work 000000462 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument 000000462 980__ $$aTheses and Dissertations