TY  - GEN
AB  - The mechanisms that regulate gene expression are complex, however many features have  been well-conserved through evolution.  This dissertation discusses three main topics: (1) the genomic structure of the RGM family of genes, (2) the mechanisms of transcriptional and post-transcriptional regulation focusing on RGMc, and (3) the molecular evolution of the RGM family.  The long-range and overarching goal of this dissertation is to enhance understanding of the molecular mechanisms by which evolution has shaped the regulation of gene expression in a family of genes, like the RGM family.
AD  - Oregon Health and Science University
AU  - Severyn, Christopher
DA  - 2010-07-01
DO  - 10.6083/M40K26J3
DO  - DOI
ED  - Rotwein, Peter
ED  - Advisor
ID  - 502
KW  - Membrane Proteins
KW  - Nerve Tissue Proteins
KW  - Muscle Proteins
KW  - Bone Morphogenetic Proteins
KW  - Myogenin
KW  - Gene Expression Regulation
KW  - Axon Guidance
KW  - Hemochromatosis Protein
KW  - Hemochromatosis
KW  - Gene Expression
KW  - Iron
KW  - Evolution, Molecular
KW  - repulsive guidance molecule
L1  - https://digitalcollections.ohsu.edu/record/502/files/503_etd.pdf
L2  - https://digitalcollections.ohsu.edu/record/502/files/503_etd.pdf
L4  - https://digitalcollections.ohsu.edu/record/502/files/503_etd.pdf
LK  - https://digitalcollections.ohsu.edu/record/502/files/503_etd.pdf
N2  - The mechanisms that regulate gene expression are complex, however many features have  been well-conserved through evolution.  This dissertation discusses three main topics: (1) the genomic structure of the RGM family of genes, (2) the mechanisms of transcriptional and post-transcriptional regulation focusing on RGMc, and (3) the molecular evolution of the RGM family.  The long-range and overarching goal of this dissertation is to enhance understanding of the molecular mechanisms by which evolution has shaped the regulation of gene expression in a family of genes, like the RGM family.
PB  - Oregon Health and Science University
PY  - 2010-07-01
T1  - Regulation and evolutionary origins of repulsive guidance molecule C / hemojuvelin expression: a muscle-enriched gene involved in iron metabolism
TI  - Regulation and evolutionary origins of repulsive guidance molecule C / hemojuvelin expression: a muscle-enriched gene involved in iron metabolism
UR  - https://digitalcollections.ohsu.edu/record/502/files/503_etd.pdf
Y1  - 2010-07-01
ER  -