000000505 001__ 505
000000505 005__ 20260304105455.0
000000505 0247_ $$2DOI$$a10.6083/M4M906M2
000000505 037__ $$aETD
000000505 245__ $$aThe postprandial excursion of total and undercarboxylated osteocalcin concentration following low versus high complex carbohydrate meals in the healthy weight adult
000000505 260__ $$bOregon Health and Science University
000000505 269__ $$a2009
000000505 336__ $$aThesis
000000505 502__ $$bM.S.
000000505 520__ $$aOsteocalcin, a bone‑derived protein, may influence glucose regulation, adiponectin levels, and pancreatic β‑cell activity, with its undercarboxylated form potentially acting as an endocrine hormone. Dietary composition may affect both total and undercarboxylated osteocalcin, yet the acute impact of different macronutrient patterns remains unclear. This randomized crossover study examined postprandial responses to low‑carbohydrate (LC) versus high–complex carbohydrate (HC) meals in ten healthy adults. Participants completed two three‑day run‑in periods followed by LC or HC test meals, with hourly blood sampling to measure total and undercarboxylated osteocalcin via ELISA. Findings may help clarify dietary effects on osteocalcin and support nutrition interventions for obesity, osteoporosis, and diabetes.
000000505 540__ $$fCC BY
000000505 542__ $$fIn copyright - single owner
000000505 650__ $$aDiet, Carbohydrate-Restricted$$036410
000000505 650__ $$aOsteocalcin$$028567
000000505 650__ $$aOsteoporosis$$023359
000000505 650__ $$aObesity$$023118
000000505 650__ $$aDiabetes Mellitus$$017671
000000505 650__ $$aCross-Over Studies$$030934
000000505 650__ $$aDiet, Sodium-Restricted$$017783
000000505 691__ $$aSchool of Medicine$$041369
000000505 692__ $$aGraduate Programs in Human Nutrition$$041470
000000505 7001_ $$aSmith, Julie$$uOregon Health and Science University$$041354
000000505 8564_ $$9e4a29627-e230-4d8e-84f1-b3c1fea1e73f$$s593303$$uhttps://digitalcollections.ohsu.edu/record/505/files/506_etd.pdf$$ePublic$$2f42f2027813c1de81803354bfe898328$$31
000000505 905__ $$a/rest/prod/nz/80/5z/73/nz805z73k
000000505 909CO $$ooai:digitalcollections.ohsu.edu:505$$pstudent-work
000000505 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument
000000505 980__ $$aTheses and Dissertations