000000521 001__ 521 000000521 005__ 20260303105835.0 000000521 0247_ $$2DOI$$a10.6083/M4JD4TR7 000000521 037__ $$aETD 000000521 245__ $$aRetrospective analysis of Clostridium difficile-associated disease at Oregon Health & Science University 000000521 269__ $$a2009 000000521 336__ $$aThesis 000000521 502__ $$bM.P.H. 000000521 520__ $$aClostridium difficile associated disease (CDAD) consists of severe diarrhea, fever, lower abdominal pain, anorexia, nausea, malaise and leukocytosis. Over the last few years, increasing incidence and severity of Clostridium difficile infections have been documented in hospitalized settings. The bone marrow transplant (BMT) population is one assumed to be at increased risk for Clostridium difficile infection due to the high levels of immunosuppression, in addition to prolonged and frequent hospitalizations. We undertook this study to see if incidence of CDAD has increased in our high risk BMT population and identify potential risk factors that may be modified to prevent disease in the future. The objectives of the current study are to analyze clinical data collected from OHSU’s BMT population to 1) describe the burden and outcomes of CDAD in this BMT population; 2) to evaluate patient and epidemiologic factors associated with CDAD. 000000521 540__ $$fCC BY 000000521 542__ $$fIn copyright - single owner 000000521 650__ $$aBone Marrow Transplantation$$028830 000000521 650__ $$aContraindications$$012447 000000521 650__ $$aClostridium Infections$$016815 000000521 650__ $$aClostridioides difficile$$029096 000000521 691__ $$aSchool of Medicine$$041369 000000521 692__ $$aDepartment of Public Health and Preventive Medicine$$041444 000000521 7001_ $$aVarley, Cara$$uOregon Health and Science University$$041354 000000521 8564_ $$9e6eab032-9fb3-41a2-a7f5-b2235df31223$$s916504$$uhttps://digitalcollections.ohsu.edu/record/521/files/522_etd.pdf$$ePublic$$28a158038d3100c4c873dbd2c1deeeada$$31 000000521 905__ $$a/rest/prod/54/25/k9/71/5425k9713 000000521 909CO $$ooai:digitalcollections.ohsu.edu:521$$pstudent-work 000000521 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument 000000521 980__ $$aTheses and Dissertations