000000526 001__ 526
000000526 005__ 20260224084349.0
000000526 0247_ $$2DOI$$a10.6083/M4WM1BCJ
000000526 037__ $$aETD
000000526 245__ $$aRelationships between baseline fasting glucose and insulin status, type 2 diabetes, and incident prostate cancer in the Osteoporotic Fractures in Men Study (MrOS)
000000526 260__ $$bOregon Health and Science University
000000526 269__ $$a2010
000000526 336__ $$aThesis
000000526 502__ $$bM.P.H.
000000526 520__ $$aObesity, type 2 diabetes, and prostate cancer have risen in recent years, raising questions about shared biological pathways. In a cohort of 5,995 men from the Osteoporotic Fractures in Men Study followed for eight years, we examined fasting glucose, fasting insulin, and type 2 diabetes in relation to incident prostate cancer. Impaired fasting glucose was not associated with increased risk, but higher fasting insulin levels were linked to greater prostate cancer risk. In contrast, men with type 2 diabetes showed a lower risk. These findings suggest complex, differing roles for insulin signaling and glucose metabolism in prostate cancer development.
000000526 540__ $$fCC BY
000000526 542__ $$fIn copyright - single owner
000000526 650__ $$aProstatic Neoplasms$$024731
000000526 650__ $$aFasting$$018901
000000526 650__ $$aInsulin$$020872
000000526 650__ $$aDiabetes Mellitus, Type 2$$017675
000000526 650__ $$aMen$$022015
000000526 650__ $$aObesity$$023118
000000526 650__ $$aBlood Glucose$$015661
000000526 650__ $$aProstatic Neoplasms$$024731
000000526 650__ $$aLung Neoplasms$$021651
000000526 650__ $$aColorectal Neoplasms$$028197
000000526 650__ $$aOsteoporotic Fractures$$039374
000000526 650__ $$aMale$$021762
000000526 650__ $$aAged$$014351
000000526 6531_ $$amros
000000526 6531_ $$aprospective cohort
000000526 6531_ $$afasting glucose and insulin
000000526 691__ $$aSchool of Medicine$$041369
000000526 692__ $$aDepartment of Public Health and Preventive Medicine$$041444
000000526 7001_ $$aKovvali, Sirisha$$uOregon Health and Science University$$041354
000000526 8564_ $$90235c34b-8cd2-49e5-8259-f4f584691e53$$s1660161$$uhttps://digitalcollections.ohsu.edu/record/526/files/527_etd.pdf$$ePublic$$21ce368e05d7232940a74a9cbed620282$$31
000000526 905__ $$a/rest/prod/bc/38/6j/21/bc386j21m
000000526 909CO $$ooai:digitalcollections.ohsu.edu:526$$pstudent-work
000000526 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument
000000526 980__ $$aTheses and Dissertations