000000551 001__ 551 000000551 005__ 20260220131126.0 000000551 0247_ $$2DOI$$a10.6083/M4NZ85N0 000000551 037__ $$aETD 000000551 245__ $$aRedefining the gold standard for diagnosis and risk factor analysis in cervical dysplasia 000000551 260__ $$bOregon Health and Science University 000000551 269__ $$a2010 000000551 336__ $$aThesis 000000551 502__ $$bM.P.H. 000000551 520__ $$aCervical intraepithelial neoplasia (CIN) diagnostic methods are suboptimal due to limitations in reproducibility and accuracy, which affects clinical management and understanding of risk factors for CIN. These limitations are especially relevant for the histologic diagnosis of moderate dysplasia (CIN 2). We hypothesize that molecular markers, such as p16 and Ki-67, may improve diagnostic reproducibility and accuracy and also lead to a better understanding of cervical cancer epidemiology. 000000551 540__ $$fCC BY 000000551 542__ $$fIn copyright - single owner 000000551 650__ $$aDiagnosis$$017684 000000551 650__ $$aObserver Variation$$028500 000000551 650__ $$aPapillomaviridae$$033350 000000551 650__ $$aUterine Cervical Dysplasia$$016399 000000551 691__ $$aSchool of Medicine$$041369 000000551 692__ $$aDepartment of Public Health and Preventive Medicine$$041444 000000551 7001_ $$aKing, Emily$$uOregon Health and Science University$$041354 000000551 7201_ $$aMorgan, Terry$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor 000000551 8564_ $$923b1e245-4005-411a-8745-26bfd38ad00f$$s1495999$$uhttps://digitalcollections.ohsu.edu/record/551/files/552_etd.pdf$$ePublic$$2a6672ae9d1addd57f686593c2666b62c$$31 000000551 905__ $$a/rest/prod/3n/20/3z/11/3n203z11f 000000551 909CO $$ooai:digitalcollections.ohsu.edu:551$$pstudent-work 000000551 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument 000000551 980__ $$aTheses and Dissertations