@article{ETD,
      recid = {559},
      author = {Bernardi, Rick},
      title = {The role of adrenergic receptors in the potential  reconsolidation of a cocaine conditioned place preference},
      publisher = {Oregon Health and Science University},
      school = {Ph.D.},
      address = {2009},
      number = {ETD},
      abstract = {Disrupting memory after retrieval is thought to reflect  impairment of reconsolidation, a process that restabilizes  memories and can sustain drug cue–controlled behavior.  Because drug‑associated stimuli contribute to persistent  addiction, pharmacologically targeting reconsolidation is a  promising therapeutic strategy. This dissertation  investigates the role of the noradrenergic system in  reconsolidation of drug memories using the conditioned  place preference (CPP) paradigm. Adrenergic receptor  antagonists were administered systemically and directly  into the basolateral amygdala, a key reconsolidation locus.  We evaluated whether blocking noradrenergic signaling at  retrieval attenuates subsequent CPP expression, thereby  weakening drug cue–memory strength. Findings aim to clarify  noradrenergic mechanisms that support reconsolidation and  to identify adrenergic targets with potential for  pharmacotherapies that reduce the motivational impact of  drug‑paired cues.},
      url = {http://digitalcollections.ohsu.edu/record/559},
      doi = {https://doi.org/10.6083/M4N014HG},
}