000000564 001__ 564
000000564 005__ 20260302125019.0
000000564 0247_ $$2DOI$$a10.6083/M4086394
000000564 037__ $$aETD
000000564 245__ $$aNomogram predictive of 10-year cause-specific mortality in differentiated thyroid cancer
000000564 260__ $$bOregon Health and Science University
000000564 269__ $$a2009
000000564 336__ $$aThesis
000000564 502__ $$bM.P.H.
000000564 520__ $$aAccurate risk stratification is essential for guiding treatment decisions in differentiated thyroid cancer (DTC). Although numerous population‑level risk factors for DTC mortality have been identified, they have not been integrated into a tool for individualized prediction. This study developed a nomogram to estimate 10‑year cause‑specific mortality using a historical SEER cohort of 9,654 patients diagnosed between 1985 and 1995. Multivariable Cox regression identified age, gender, extracapsular extension, tumor size, nodal involvement, distant metastasis, and histology as significant predictors. The resulting nomogram demonstrated excellent discrimination (AUC = 0.93) and calibration. This tool provides the first individualized prognostic model for DTC and may improve clinical decision‑making and research stratification.
000000564 540__ $$fCC BY
000000564 542__ $$fIn copyright - single owner
000000564 650__ $$aThyroid Neoplasms$$027071
000000564 650__ $$aMortality$$022435
000000564 650__ $$aNomograms$$036205
000000564 650__ $$aClinical Decision-Making$$011067
000000564 650__ $$aRisk Assessment$$030914
000000564 650__ $$aSEER Program$$030790
000000564 691__ $$aSchool of Medicine$$041369
000000564 692__ $$aDepartment of Public Health and Preventive Medicine$$041444
000000564 7001_ $$aPark, Renee$$uOregon Health and Science University$$041354
000000564 7201_ $$aGross, Neil$$uOregon Health and Science University$$041354$$7Personal$$eMentor
000000564 8564_ $$952f75e15-2229-457f-a366-43b708c8cd6d$$s1479805$$uhttps://digitalcollections.ohsu.edu/record/564/files/565_etd.pdf$$ePublic$$20fa178209e2694c3b3adc1aafea9dd12$$31
000000564 905__ $$a/rest/prod/gx/41/mh/88/gx41mh887
000000564 909CO $$ooai:digitalcollections.ohsu.edu:564$$pstudent-work
000000564 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument
000000564 980__ $$aTheses and Dissertations