TY  - THES
AB  - This study examined whether Giardia intestinalis infection alters the risk of subsequent Cyclospora cayetanensis or Cryptosporidium infection in Peruvian children. Using data from a five‑year prospective cohort of 477 children, we assessed infection frequency, symptom patterns, treatment rates, and risk factors. One‑third of children had Giardia within 60 days of enrollment, and nearly 80% experienced infection during the study. Cox proportional hazards analysis showed that Giardia infection significantly increased the risk of later Cryptosporidium infection, and also increased the risk of Cyclospora infection, with stronger effects in households lacking toilets. Treatment of Giardia did not change these risks. Findings suggest Giardia may predispose children to subsequent protozoal infections, underscoring the need for further investigation of environmental and socioeconomic risk factors.
AD  - Oregon Health and Science University
AU  - Ross, Jennifer
DA  - 2009
DO  - 10.6083/M4QR4V34
DO  - DOI
ED  - Choi, Dongseok
ED  - Cama, Vitaliano
ED  - Advisor
ED  - Advisor
ID  - 566
KW  - Infant
KW  - Population Groups
KW  - Cyclospora
KW  - Giardia lamblia
KW  - Cryptosporidium
KW  - Child
KW  - Prospective Studies
KW  - Socioeconomic Factors
KW  - Giardiasis
L1  - https://digitalcollections.ohsu.edu/record/566/files/567_etd.pdf
L2  - https://digitalcollections.ohsu.edu/record/566/files/567_etd.pdf
L4  - https://digitalcollections.ohsu.edu/record/566/files/567_etd.pdf
LK  - https://digitalcollections.ohsu.edu/record/566/files/567_etd.pdf
N2  - This study examined whether Giardia intestinalis infection alters the risk of subsequent Cyclospora cayetanensis or Cryptosporidium infection in Peruvian children. Using data from a five‑year prospective cohort of 477 children, we assessed infection frequency, symptom patterns, treatment rates, and risk factors. One‑third of children had Giardia within 60 days of enrollment, and nearly 80% experienced infection during the study. Cox proportional hazards analysis showed that Giardia infection significantly increased the risk of later Cryptosporidium infection, and also increased the risk of Cyclospora infection, with stronger effects in households lacking toilets. Treatment of Giardia did not change these risks. Findings suggest Giardia may predispose children to subsequent protozoal infections, underscoring the need for further investigation of environmental and socioeconomic risk factors.
PY  - 2009
T1  - Giardia intestinalis infection as a risk factor for Cyclospora cayetanensis and Cryptosporidium infections in Peruvian children
TI  - Giardia intestinalis infection as a risk factor for Cyclospora cayetanensis and Cryptosporidium infections in Peruvian children
UR  - https://digitalcollections.ohsu.edu/record/566/files/567_etd.pdf
Y1  - 2009
ER  -