000000566 001__ 566 000000566 005__ 20260410124448.0 000000566 0247_ $$2DOI$$a10.6083/M4QR4V34 000000566 037__ $$aETD 000000566 245__ $$aGiardia intestinalis infection as a risk factor for Cyclospora cayetanensis and Cryptosporidium infections in Peruvian children 000000566 269__ $$a2009 000000566 336__ $$aThesis 000000566 502__ $$bM.P.H. 000000566 520__ $$aThis study examined whether Giardia intestinalis infection alters the risk of subsequent Cyclospora cayetanensis or Cryptosporidium infection in Peruvian children. Using data from a five‑year prospective cohort of 477 children, we assessed infection frequency, symptom patterns, treatment rates, and risk factors. One‑third of children had Giardia within 60 days of enrollment, and nearly 80% experienced infection during the study. Cox proportional hazards analysis showed that Giardia infection significantly increased the risk of later Cryptosporidium infection, and also increased the risk of Cyclospora infection, with stronger effects in households lacking toilets. Treatment of Giardia did not change these risks. Findings suggest Giardia may predispose children to subsequent protozoal infections, underscoring the need for further investigation of environmental and socioeconomic risk factors. 000000566 540__ $$fCC BY 000000566 542__ $$fIn copyright - single owner 000000566 650__ $$aInfant$$020774 000000566 650__ $$aPopulation Groups$$035461 000000566 650__ $$aCyclospora$$032895 000000566 650__ $$aGiardia lamblia$$029445 000000566 650__ $$aCryptosporidium$$017231 000000566 650__ $$aChild$$016462 000000566 650__ $$aProspective Studies$$024706 000000566 650__ $$aSocioeconomic Factors$$026134 000000566 650__ $$aGiardiasis$$019514 000000566 651__ $$aPeru$$041104 000000566 691__ $$aSchool of Medicine$$041369 000000566 692__ $$aDepartment of Public Health and Preventive Medicine$$041444 000000566 7001_ $$aRoss, Jennifer$$uOregon Health and Science University$$041354 000000566 7201_ $$aChoi, Dongseok$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor 000000566 7201_ $$aCama, Vitaliano$$uJohns Hopkins Bloomberg School of Public Health$$7Personal$$eAdvisor 000000566 8564_ $$93c9f067a-7b4a-4717-a9f4-3a40ddfcf38d$$s298916$$uhttps://digitalcollections.ohsu.edu/record/566/files/567_etd.pdf$$ePublic$$258af87b8fe0163d89fcfa0915d5c65d5$$31 000000566 901__ $$a<p>These documents are archival records. They are retained for historical reference only. </p><p><b>Need an accessible version? Use the ‘Get Accessible Copy’ link above.</b></p> 000000566 905__ $$a/rest/prod/kh/04/dp/73/kh04dp73w 000000566 909CO $$ooai:digitalcollections.ohsu.edu:566$$pstudent-work 000000566 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument 000000566 980__ $$aTheses and Dissertations