000000575 001__ 575 000000575 005__ 20260302120132.0 000000575 0247_ $$2DOI$$a10.6083/M4K07285 000000575 037__ $$aETD 000000575 245__ $$aImpact of regional and racial variation in extent of lymph node dissection on survival in pancreatic adenocarcinoma: a SEER database analysis 000000575 260__ $$bOregon Health and Science University 000000575 269__ $$a2009 000000575 336__ $$aThesis 000000575 502__ $$bM.P.H. 000000575 520__ $$aThis study examined racial and regional differences in lymph node assessment and overall survival among 3,106 patients who underwent surgical resection for pancreatic adenocarcinoma using SEER 9 data (1988–2005). Most patients (68%) had fewer than 12 lymph nodes resected, indicating inadequate lymph node assessment (ALNA). While no racial differences were observed in node‑negative patients, significant variation emerged among node‑positive patients, particularly in those with high lymph node ratios (LNR > 0.4). African American patients had significantly poorer survival compared to White and Asian/Pacific Islander patients. Regional differences in the extent of lymph node dissection were also marked. Overall, inadequate lymph node assessment and racial disparities were strong predictors of survival, underscoring the need for improved staging and equitable care in pancreatic cancer treatment. 000000575 540__ $$fCC BY 000000575 542__ $$fIn copyright - single owner 000000575 650__ $$aSEER Program$$030790 000000575 650__ $$aPancreatic Neoplasms$$023517 000000575 650__ $$aLymph Node Excision$$021672 000000575 650__ $$aLymph Nodes$$021673 000000575 650__ $$aAdenocarcinoma$$014225 000000575 650__ $$aRacial Groups$$035486 000000575 691__ $$aSchool of Medicine$$041369 000000575 692__ $$aDepartment of Public Health and Preventive Medicine$$041444 000000575 7001_ $$aPatil, Meena$$uOregon Health and Science University$$041354 000000575 7201_ $$aMarshall, Lynn$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor 000000575 8564_ $$94b10cfd6-4c1b-406f-9a0a-c8f8654b19c8$$s455095$$uhttps://digitalcollections.ohsu.edu/record/575/files/576_etd.pdf$$ePublic$$22a7615290d06b7cb2eb23ff07a0516ca$$31 000000575 905__ $$a/rest/prod/fq/97/7t/82/fq977t82f 000000575 909CO $$ooai:digitalcollections.ohsu.edu:575$$pstudent-work 000000575 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument 000000575 980__ $$aTheses and Dissertations