000000646 001__ 646
000000646 005__ 20260120144837.0
000000646 0247_ $$2DOI$$a10.6083/M4D21VM1
000000646 037__ $$aETD
000000646 245__ $$aShocks and increased mortality in implantable cardioverter-defibrillator patient: impact of shock burden
000000646 260__ $$bOregon Health and Science University
000000646 269__ $$a2011
000000646 336__ $$aThesis
000000646 502__ $$bM.P.H.
000000646 502__ $$gPhysiology & Pharmacology (sunsetting)
000000646 520__ $$aICD shocks have been linked to higher mortality, but whether they directly contribute to risk is unclear. We evaluated the association between ICD shocks and survival after adjusting for baseline mortality using the Seattle Heart Failure Model. Among 425 patients followed for a median of 41 months, 59% experienced ≥1 shock and 40% died. Any shock was associated with increased mortality (HR 1.55; 95% CI 1.07–2.23). Mortality rose with greater shock burden, while antitachycardia pacing alone did not increase risk. These findings suggest ICD shocks themselves may contribute to higher mortality.
000000646 540__ $$fCC BY
000000646 542__ $$fIn copyright - single owner
000000646 650__ $$aMortality$$022435
000000646 650__ $$aDefibrillators$$035974
000000646 650__ $$aShock$$025955
000000646 650__ $$aDeath$$017403
000000646 650__ $$aDeath, Sudden, Cardiac$$029385
000000646 650__ $$aDefibrillators, Implantable$$029722
000000646 650__ $$aHeart Arrest$$019929
000000646 691__ $$aSchool of Medicine$$041369
000000646 692__ $$aDepartment of Physiology and Pharmacology$$041442
000000646 7001_ $$aLarsen, Gail$$uOregon Health and Science University$$041354
000000646 8564_ $$94f440a4a-4513-4db6-874f-7de3b6be0b23$$s270278$$uhttps://digitalcollections.ohsu.edu/record/646/files/647_etd.pdf$$ePublic$$2a669cf38e95e062a89e3358433cc7ee8$$31
000000646 905__ $$a/rest/prod/pn/89/d6/59/pn89d6592
000000646 909CO $$ooai:digitalcollections.ohsu.edu:646$$pstudent-work
000000646 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument
000000646 980__ $$aTheses and Dissertations