000000658 001__ 658 000000658 005__ 20250424232538.0 000000658 0247_ $$2DOI$$a10.6083/M4V122ST 000000658 037__ $$aETD 000000658 245__ $$aIncorporation of uncertainty into a medical decision model of erthropoietin use in premature infants at risk for red cell transfusion 000000658 260__ $$bOregon Health and Science University 000000658 269__ $$a2011 000000658 336__ $$aCapstone 000000658 502__ $$bM.B.I. 000000658 502__ $$gClinical Informatics 000000658 520__ $$aPremature infants are at risk of developing significant anemia with adverse clinical outcome, yet blood transfusions used to treat anemia carry additional risks. Studies have investigated the use of recombinant erythropoietin (r-Epo) to reduce the need for blood transfusions. The beneficial impact of r-Epo use is controversial, and the original studies and meta-analyses were hampered by significant heterogeneity across trials, particularly in gestational age/birth weight, r-Epo dose, and transfusion criteria, as well as variation in the quality of evidence. 000000658 540__ $$fCC BY 000000658 542__ $$fIn copyright - single owner 000000658 650__ $$aInfant$$020774 000000658 650__ $$aErythropoietin$$018620 000000658 650__ $$aCost-Benefit Analysis$$017144 000000658 650__ $$aInfant, Premature$$020785 000000658 650__ $$aBlood Transfusion$$015678 000000658 650__ $$aAnemia$$014696 000000658 6531_ $$acost effectiveness 000000658 6531_ $$arecombinant erythropoieti 000000658 691__ $$aSchool of Medicine$$041369 000000658 692__ $$aDepartment of Medical Informatics and Clinical Epidemiology$$041422 000000658 7001_ $$aMerrill, Jeffrey$$uOregon Health and Science University$$041354 000000658 7201_ $$aEden, Karen$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor 000000658 8564_ $$9164da49a-37e6-402c-9435-efa27fb715c1$$s561149$$uhttps://digitalcollections.ohsu.edu/record/658/files/659_etd.pdf$$ePublic$$289e3d5dfe98a459c4a47ad0095579bce$$31 000000658 905__ $$a/rest/prod/54/25/k9/73/5425k973n 000000658 909CO $$ooai:digitalcollections.ohsu.edu:658$$pstudent-work 000000658 980__ $$aBiomedical Informatics