@article{ETD, recid = {725}, author = {Spinelli, Kateri}, title = {Molecular characterization of hair cell metabolism and tip link damage}, publisher = {Oregon Health and Science University}, school = {Ph.D.}, address = {2012}, number = {ETD}, abstract = {Inner ear hair cells are essential for hearing, balance, and acceleration, yet they do not regenerate in humans, making their maintenance critical for preventing age-related hearing loss. The molecular mechanisms underlying normal hair-cell function and recovery from damage remain poorly understood. This study characterizes energy metabolism in hair cells of chicken auditory and vestibular organs and examines cellular responses to hair-bundle tip link damage. Findings provide insight into metabolic processes and repair mechanisms that support hair-cell resilience, offering a foundation for strategies to preserve sensory function and mitigate hearing loss.}, url = {http://digitalcollections.ohsu.edu/record/725}, doi = {https://doi.org/10.6083/M4XG9P5Z}, }