000000740 001__ 740
000000740 005__ 20251218093052.0
000000740 0247_ $$2DOI$$a10.6083/M40C4SSZ
000000740 037__ $$aETD
000000740 245__ $$aMRI detection of early-stage cerebral cortical abnormalities caused by fetal exposure to alcohol
000000740 260__ $$bOregon Health and Science University
000000740 269__ $$a2012
000000740 336__ $$aDissertation
000000740 502__ $$bPh.D.
000000740 502__ $$gBehavioral & Systems Neuroscience
000000740 520__ $$aFetal Alcohol Spectrum Disorder (FASD) encompasses conditions caused by prenatal alcohol exposure, leading to lifelong cognitive and behavioral impairments. Current diagnosis relies on physical and neurological indicators, often identified years after birth, delaying intervention. Early detection is critical to reduce adverse outcomes, yet remains challenging due to symptom variability and overlap with other disorders. This research explores novel approaches for early FASD diagnosis by examining cerebral cortex development, a period highly sensitive to alcohol exposure and essential for future behavioral function. Findings aim to improve early identification strategies and inform therapeutic interventions during critical developmental windows.
000000740 540__ $$fCC BY
000000740 542__ $$fIn copyright - single owner
000000740 650__ $$aMalformations of Cortical Development$$037724
000000740 650__ $$aEthanol$$014406
000000740 650__ $$aMagnetic Resonance Imaging$$021747
000000740 650__ $$aDiffusion Tensor Imaging$$038582
000000740 650__ $$aPrenatal Exposure Delayed Effects$$024568
000000740 650__ $$aPregnancy$$024523
000000740 650__ $$aFetal Alcohol Spectrum Disorders$$040252
000000740 6531_ $$adevelopmental neurobiology
000000740 691__ $$aSchool of Medicine$$041369
000000740 692__ $$aDepartment of Behavioral Neuroscience$$041394
000000740 7001_ $$aLeigland, Lindsey$$uOregon Health and Science University$$041354
000000740 7201_ $$aKroenke, Christopher$$uOregon Health and Science University$$041354$$7Personal$$eMentor
000000740 8564_ $$91f3a1068-6b7c-4065-a3fe-4e255bba2f47$$s2305515$$uhttps://digitalcollections.ohsu.edu/record/740/files/743_etd.pdf$$ePublic$$259e837debea3a62a5bcd33cf6fd543e3$$31
000000740 905__ $$a/rest/prod/f4/75/2g/72/f4752g72m
000000740 909CO $$ooai:digitalcollections.ohsu.edu:740$$pstudent-work
000000740 980__ $$aTheses and Dissertations