TY  - GEN
N2  - This dissertation investigates two unique phenomena, neurotransmitter co-release and neural oscillations, in early auditory regions where they have not been observed before. Co-release and oscillations are common processes in other brain regions, where they are thought to expand the computational capacity of local circuits. We investigated co-release of two inhibitory neurotransmitters in the inferior colliculus, the midbrain hub for auditory processing. We also established the presence of slow oscillations in the principal neurons of the dorsal cochlear nucleus (DCN), a key brainstem nucleus that integrates auditory input from the ear with multisensory information. Both lines of research utilized patch-clamp electrophysiological recordings from in vitro slices of mouse brainstem and midbrain. This dissertation reveals new mechanisms for how auditory information is processed by local brainstem and midbrain circuits.
DO  - 10.6083/vt150j93m
DO  - DOI
AB  - This dissertation investigates two unique phenomena, neurotransmitter co-release and neural oscillations, in early auditory regions where they have not been observed before. Co-release and oscillations are common processes in other brain regions, where they are thought to expand the computational capacity of local circuits. We investigated co-release of two inhibitory neurotransmitters in the inferior colliculus, the midbrain hub for auditory processing. We also established the presence of slow oscillations in the principal neurons of the dorsal cochlear nucleus (DCN), a key brainstem nucleus that integrates auditory input from the ear with multisensory information. Both lines of research utilized patch-clamp electrophysiological recordings from in vitro slices of mouse brainstem and midbrain. This dissertation reveals new mechanisms for how auditory information is processed by local brainstem and midbrain circuits.
T1  - Synaptic transmission and electrical resonance in early auditory processing
DA  - 2019
AU  - Moore, Lucille
L1  - https://digitalcollections.ohsu.edu/record/7461/files/moore.lucille.2019.pdf
PB  - Oregon Health and Science University
PY  - 2019
ID  - 7461
L4  - https://digitalcollections.ohsu.edu/record/7461/files/moore.lucille.2019.pdf
KW  - Inferior Colliculi
KW  - Neurons
KW  - Mice
KW  - Reticular Formation
KW  - Glycine
KW  - Membrane Potentials
KW  - brainstem
TI  - Synaptic transmission and electrical resonance in early auditory processing
Y1  - 2019
L2  - https://digitalcollections.ohsu.edu/record/7461/files/moore.lucille.2019.pdf
LK  - https://digitalcollections.ohsu.edu/record/7461/files/moore.lucille.2019.pdf
UR  - https://digitalcollections.ohsu.edu/record/7461/files/moore.lucille.2019.pdf
ER  -