000007536 001__ 7536
000007536 005__ 20231129124941.0
000007536 0247_ $$2DOI$$a10.6083/x346d473s
000007536 037__ $$aETD
000007536 245__ $$aThe relationship between sociality and alcohol consumption in the prairie vole rodent model
000007536 260__ $$bOregon Health and Science University
000007536 269__ $$a2019
000007536 336__ $$aDissertation
000007536 502__ $$bPh.D.
000007536 520__ $$aAlcohol use disorder (AUD) affects millions of people each year and is heavily influenced by social networks. On the other hand, social networks are dramatically influenced by alcohol consumption. Understanding the interaction between sociality and alcohol consumption is important to prevent and treat AUD. Rodent models have been useful to study the interaction between sociality and alcohol consumption. Traditionally the laboratory mouse and rat have been used as the main animal models of study. However, these traditional animal models are difficult to use to model human social relationships because they do not form strong social bonds with conspecifics. Therefore, our laboratory and others have used the prairie vole (Microtus ochrogaster) to explore the interactions between sociality and alcohol use because prairie voles have high predictive validity for human social behaviors and will consume high levels of alcohol voluntarily. The aim of this dissertation is to explore the relationship between alcohol use and sociality and further develop the prairie vole rodent model to study the efficacy of oxytocin as a pharmacotherapy for AUD.
000007536 542__ $$fIn copyright - single owner
000007536 6531_ $$aneuroscience
000007536 6531_ $$asocial neuroscience
000007536 6531_ $$aaddiction
000007536 6531_ $$arodent
000007536 6531_ $$asubstance
000007536 6531_ $$aalcohol consumption
000007536 691__ $$aSchool of Medicine$$041369
000007536 692__ $$aDepartment of Behavioral Neuroscience$$041394
000007536 7001_ $$aWalcott, André T.
000007536 8564_ $$9a0f20355-143e-447f-85a1-bec4079a0903$$s5344207$$uhttps://digitalcollections.ohsu.edu/record/7536/files/walcott.andre.2019.pdf
000007536 905__ $$a/rest/prod/x3/46/d4/73/x346d473s
000007536 909CO $$ooai:digitalcollections.ohsu.edu:7536$$pstudent-work
000007536 980__ $$aTheses and Dissertations