@article{ETD, school = {Ph.D.}, author = {Hitchcock, Leah}, url = {http://digitalcollections.ohsu.edu/record/7573}, title = {Involvement of the dorsal hippocampus and histone deacetylase 3 in reward-seeking behaviors}, publisher = {Oregon Health and Science University}, abstract = {Substance use disorder is a chronic, often relapsing disease that can include a loss of behavioral inhibition and compulsive drug-seeking. Acquisition of a reward seeking behavior often begins when cues are paired with rewards. These cues are thought to influence subsequent extinction (animal model of exposure-based therapy) and relapse-like behavior, both in humans and animals. My work found that acquisition and extinction of cocaine-induced conditioned place preference (CPP) were sensitive to the configuration of the apparatus and that the dorsal hippocampus (DH) regulated expression of CPP after acquisition and extinction.}, number = {ETD}, doi = {https://doi.org/10.6083/m4hm580w}, recid = {7573}, address = {2017}, }